Ontogeny of brain neurotensin in the rat: A radioimmunoassay study

G. Bissette, C. Richardson, J. S. Kizer, Charles Nemeroff

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Concentrations of neurotensin-like immunoreactivity in several discrete brain areas were measured by radioimmunoassay in rats of different ages (2, 5, 10, 20, 30, and 60 days). Neurotensin-like immunoreactivity increased steadily from 2 to 30 days of age in the hypothalamus and then plateaued, while the preoptic area and amygdala concentrations peaked at 30 days of age. Brainstem neurotensin-like immunoreactivity concentrations increased from 2 to 10 days of age and decreased from 20 to 60 days of age. Several other regions showed no significant age-associated changes in neurotensin-like immunoreactivity.

Original languageEnglish
Pages (from-to)283-287
Number of pages5
JournalJournal of Neurochemistry
Volume43
Issue number1
StatePublished - Jan 1 1984
Externally publishedYes

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Neurotensin
Radioimmunoassay
Rats
Brain
Preoptic Area
Amygdala
Hypothalamus
Brain Stem
neurotensin-like immunoreactivity

ASJC Scopus subject areas

  • Biochemistry
  • Cellular and Molecular Neuroscience

Cite this

Ontogeny of brain neurotensin in the rat : A radioimmunoassay study. / Bissette, G.; Richardson, C.; Kizer, J. S.; Nemeroff, Charles.

In: Journal of Neurochemistry, Vol. 43, No. 1, 01.01.1984, p. 283-287.

Research output: Contribution to journalArticle

Bissette, G, Richardson, C, Kizer, JS & Nemeroff, C 1984, 'Ontogeny of brain neurotensin in the rat: A radioimmunoassay study', Journal of Neurochemistry, vol. 43, no. 1, pp. 283-287.
Bissette, G. ; Richardson, C. ; Kizer, J. S. ; Nemeroff, Charles. / Ontogeny of brain neurotensin in the rat : A radioimmunoassay study. In: Journal of Neurochemistry. 1984 ; Vol. 43, No. 1. pp. 283-287.
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