On the tryptophan residue in porcine LH and FSH-releasing hormone

Yoshihiko Baba; Akira Arimura; Andrew V. Schally

doi:10.1016/0006-291X(71)90844-8

On the tryptophan residue in porcine LH and FSH-releasing hormone

Yoshihiko Baba, Akira Arimura, Andrew V. Schally

Research output: Contribution to journal › Article

7 Scopus citations

Abstract

The effect of 2-hydroxy-5-nitrobenzyl bromide on the biological activity of a preparation of pure porcine LH and FSH-releasing hormone (LH-RH/FSH-RH) was reinvestigated. Since this treatment as well as performic acid and incubation with anhydrous trifluoroacetic acid, caused a complete inactivation of LH-RH/FSH-RH, tryptophan residue is thought to be essential for the biological activity of this polypeptide.

Original language	English (US)
Pages (from-to)	483-487
Number of pages	5
Journal	Biochemical and biophysical research communications
Volume	45
Issue number	2
DOIs	https://doi.org/10.1016/0006-291X(71)90844-8
State	Published - Oct 15 1971
Externally published	Yes

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology
Cell Biology

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Baba, Y., Arimura, A., & Schally, A. V. (1971). On the tryptophan residue in porcine LH and FSH-releasing hormone. Biochemical and biophysical research communications, 45(2), 483-487. https://doi.org/10.1016/0006-291X(71)90844-8

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