Abstract
Pro-opiomelanocortin (POMC) is the precursor of ACTH, α-MSH and β-endorphin, neuropeptides with multiple regulatory functions. Both the pituitary gland and peripheral tissues such as mammalian skin are capable of generating POMC-derived neuropeptides. Mammalian skin is also a target for POMC products; their possible roles in skin physiology and pathology are discussed in this communication.
| Original language | English (US) |
|---|---|
| Pages (from-to) | C1-C6 |
| Journal | Molecular and Cellular Endocrinology |
| Volume | 93 |
| Issue number | 1 |
| DOIs | |
| State | Published - May 1993 |
| Externally published | Yes |
Keywords
- Adrenocorticotropin
- Endorphin
- Melanotropin
- Pro-opiomelanocortin
- Skin
- Stress
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology
- Endocrinology
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Cite this
Slominski, A., Paus, R., & Wortsman, J. (1993). On the potential role of proopiomelanocortin in skin physiology and pathology. Molecular and Cellular Endocrinology, 93(1), C1-C6. https://doi.org/10.1016/0303-7207(93)90131-3