On the potential role of proopiomelanocortin in skin physiology and pathology

Andrzej Slominski; Ralf Paus; Jacobo Wortsman

doi:10.1016/0303-7207(93)90131-3

On the potential role of proopiomelanocortin in skin physiology and pathology

Andrzej Slominski, Ralf Paus, Jacobo Wortsman

Research output: Contribution to journal › Article › peer-review

118 Scopus citations

Abstract

Pro-opiomelanocortin (POMC) is the precursor of ACTH, α-MSH and β-endorphin, neuropeptides with multiple regulatory functions. Both the pituitary gland and peripheral tissues such as mammalian skin are capable of generating POMC-derived neuropeptides. Mammalian skin is also a target for POMC products; their possible roles in skin physiology and pathology are discussed in this communication.

Original language	English (US)
Pages (from-to)	C1-C6
Journal	Molecular and Cellular Endocrinology
Volume	93
Issue number	1
DOIs	https://doi.org/10.1016/0303-7207(93)90131-3
State	Published - May 1993
Externally published	Yes

Keywords

Adrenocorticotropin
Endorphin
Melanotropin
Pro-opiomelanocortin
Skin
Stress

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Endocrinology

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10.1016/0303-7207(93)90131-3

Cite this

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title = "On the potential role of proopiomelanocortin in skin physiology and pathology",

abstract = "Pro-opiomelanocortin (POMC) is the precursor of ACTH, α-MSH and β-endorphin, neuropeptides with multiple regulatory functions. Both the pituitary gland and peripheral tissues such as mammalian skin are capable of generating POMC-derived neuropeptides. Mammalian skin is also a target for POMC products; their possible roles in skin physiology and pathology are discussed in this communication.",

keywords = "Adrenocorticotropin, Endorphin, Melanotropin, Pro-opiomelanocortin, Skin, Stress",

author = "Andrzej Slominski and Ralf Paus and Jacobo Wortsman",

note = "Funding Information: We acknowledgeg ratefullyc ritical readingo f Dr. B. Czarnetzki and Dr. L. King, and valuable comments and editorial help of Dr. J.W. Funder. The work was supportedi n part by grants from Lawrence M. Gelb Foundation to A.S. and Deutsche Forschungsgemein-schaftt o R.P.",

year = "1993",

month = may,

doi = "10.1016/0303-7207(93)90131-3",

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T1 - On the potential role of proopiomelanocortin in skin physiology and pathology

AU - Slominski, Andrzej

AU - Paus, Ralf

AU - Wortsman, Jacobo

N1 - Funding Information: We acknowledgeg ratefullyc ritical readingo f Dr. B. Czarnetzki and Dr. L. King, and valuable comments and editorial help of Dr. J.W. Funder. The work was supportedi n part by grants from Lawrence M. Gelb Foundation to A.S. and Deutsche Forschungsgemein-schaftt o R.P.

PY - 1993/5

Y1 - 1993/5

N2 - Pro-opiomelanocortin (POMC) is the precursor of ACTH, α-MSH and β-endorphin, neuropeptides with multiple regulatory functions. Both the pituitary gland and peripheral tissues such as mammalian skin are capable of generating POMC-derived neuropeptides. Mammalian skin is also a target for POMC products; their possible roles in skin physiology and pathology are discussed in this communication.

AB - Pro-opiomelanocortin (POMC) is the precursor of ACTH, α-MSH and β-endorphin, neuropeptides with multiple regulatory functions. Both the pituitary gland and peripheral tissues such as mammalian skin are capable of generating POMC-derived neuropeptides. Mammalian skin is also a target for POMC products; their possible roles in skin physiology and pathology are discussed in this communication.

KW - Adrenocorticotropin

KW - Endorphin

KW - Melanotropin

KW - Pro-opiomelanocortin

KW - Skin

KW - Stress

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JO - Molecular and Cellular Endocrinology

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On the potential role of proopiomelanocortin in skin physiology and pathology

Abstract

Keywords

ASJC Scopus subject areas

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