On the potential role of proopiomelanocortin in skin physiology and pathology

Andrzej Slominski; Ralf Paus; Jacobo Wortsman

doi:10.1016/0303-7207(93)90131-3

On the potential role of proopiomelanocortin in skin physiology and pathology

Andrzej Slominski, Ralf Paus, Jacobo Wortsman

Dermatology & Cutaneous Surgery

Research output: Contribution to journal › Article

117 Scopus citations

Abstract

Pro-opiomelanocortin (POMC) is the precursor of ACTH, α-MSH and β-endorphin, neuropeptides with multiple regulatory functions. Both the pituitary gland and peripheral tissues such as mammalian skin are capable of generating POMC-derived neuropeptides. Mammalian skin is also a target for POMC products; their possible roles in skin physiology and pathology are discussed in this communication.

Original language	English (US)
Pages (from-to)	C1-C6
Journal	Molecular and Cellular Endocrinology
Volume	93
Issue number	1
DOIs	https://doi.org/10.1016/0303-7207(93)90131-3
State	Published - May 1993

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Keywords

Adrenocorticotropin
Endorphin
Melanotropin
Pro-opiomelanocortin
Skin
Stress

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Endocrinology

Cite this

Slominski, A., Paus, R., & Wortsman, J. (1993). On the potential role of proopiomelanocortin in skin physiology and pathology. Molecular and Cellular Endocrinology, 93(1), C1-C6. https://doi.org/10.1016/0303-7207(93)90131-3

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10.1016/0303-7207(93)90131-3