Olmesartan-Induced Enteropathy

Abimbola Adike, Juan Corral, David Rybnicek, Daniel A Sussman, Samir Shah, Eamonn Quigley

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Olmesartan-induced enteropathy mimics celiac disease clinically and pathologically. As in celiac disease, the pathologic findings are villous atrophy and increased intraepithelial lymphocytes. Clinical presentation of olmesartan-induced enteropathy includes diarrhea, weight loss, and nausea. In contrast to celiac disease, tissue transglutaminase is not elevated and there is no response to a gluten-free diet. Including this entity in the differential diagnosis of sprue-like enteropathy is critical for its early diagnosis since replacing olmesartan with an alternative antihypertensive drug can simplify the diagnostic workup and provide both clinical and histologic improvement.

Original languageEnglish (US)
Pages (from-to)230-232
Number of pages3
JournalMethodist DeBakey cardiovascular journal
Volume12
Issue number4
DOIs
StatePublished - Oct 1 2016

Fingerprint

Celiac Disease
Gluten-Free Diet
Nausea
Antihypertensive Agents
Atrophy
Weight Loss
Early Diagnosis
Diarrhea
Differential Diagnosis
Lymphocytes
olmesartan

Keywords

  • celiac disease
  • diarrhea
  • olmesartan-induced enteropathy

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Adike, A., Corral, J., Rybnicek, D., Sussman, D. A., Shah, S., & Quigley, E. (2016). Olmesartan-Induced Enteropathy. Methodist DeBakey cardiovascular journal, 12(4), 230-232. https://doi.org/10.14797/mdcj-12-4-230

Olmesartan-Induced Enteropathy. / Adike, Abimbola; Corral, Juan; Rybnicek, David; Sussman, Daniel A; Shah, Samir; Quigley, Eamonn.

In: Methodist DeBakey cardiovascular journal, Vol. 12, No. 4, 01.10.2016, p. 230-232.

Research output: Contribution to journalArticle

Adike, A, Corral, J, Rybnicek, D, Sussman, DA, Shah, S & Quigley, E 2016, 'Olmesartan-Induced Enteropathy', Methodist DeBakey cardiovascular journal, vol. 12, no. 4, pp. 230-232. https://doi.org/10.14797/mdcj-12-4-230
Adike A, Corral J, Rybnicek D, Sussman DA, Shah S, Quigley E. Olmesartan-Induced Enteropathy. Methodist DeBakey cardiovascular journal. 2016 Oct 1;12(4):230-232. https://doi.org/10.14797/mdcj-12-4-230
Adike, Abimbola ; Corral, Juan ; Rybnicek, David ; Sussman, Daniel A ; Shah, Samir ; Quigley, Eamonn. / Olmesartan-Induced Enteropathy. In: Methodist DeBakey cardiovascular journal. 2016 ; Vol. 12, No. 4. pp. 230-232.
@article{8c0df598c56848c3bdcbb6832cacd372,
title = "Olmesartan-Induced Enteropathy",
abstract = "Olmesartan-induced enteropathy mimics celiac disease clinically and pathologically. As in celiac disease, the pathologic findings are villous atrophy and increased intraepithelial lymphocytes. Clinical presentation of olmesartan-induced enteropathy includes diarrhea, weight loss, and nausea. In contrast to celiac disease, tissue transglutaminase is not elevated and there is no response to a gluten-free diet. Including this entity in the differential diagnosis of sprue-like enteropathy is critical for its early diagnosis since replacing olmesartan with an alternative antihypertensive drug can simplify the diagnostic workup and provide both clinical and histologic improvement.",
keywords = "celiac disease, diarrhea, olmesartan-induced enteropathy",
author = "Abimbola Adike and Juan Corral and David Rybnicek and Sussman, {Daniel A} and Samir Shah and Eamonn Quigley",
year = "2016",
month = "10",
day = "1",
doi = "10.14797/mdcj-12-4-230",
language = "English (US)",
volume = "12",
pages = "230--232",
journal = "Methodist DeBakey cardiovascular journal",
issn = "1947-6094",
publisher = "Methodist DeBakey Heart & Vascular Center",
number = "4",

}

TY - JOUR

T1 - Olmesartan-Induced Enteropathy

AU - Adike, Abimbola

AU - Corral, Juan

AU - Rybnicek, David

AU - Sussman, Daniel A

AU - Shah, Samir

AU - Quigley, Eamonn

PY - 2016/10/1

Y1 - 2016/10/1

N2 - Olmesartan-induced enteropathy mimics celiac disease clinically and pathologically. As in celiac disease, the pathologic findings are villous atrophy and increased intraepithelial lymphocytes. Clinical presentation of olmesartan-induced enteropathy includes diarrhea, weight loss, and nausea. In contrast to celiac disease, tissue transglutaminase is not elevated and there is no response to a gluten-free diet. Including this entity in the differential diagnosis of sprue-like enteropathy is critical for its early diagnosis since replacing olmesartan with an alternative antihypertensive drug can simplify the diagnostic workup and provide both clinical and histologic improvement.

AB - Olmesartan-induced enteropathy mimics celiac disease clinically and pathologically. As in celiac disease, the pathologic findings are villous atrophy and increased intraepithelial lymphocytes. Clinical presentation of olmesartan-induced enteropathy includes diarrhea, weight loss, and nausea. In contrast to celiac disease, tissue transglutaminase is not elevated and there is no response to a gluten-free diet. Including this entity in the differential diagnosis of sprue-like enteropathy is critical for its early diagnosis since replacing olmesartan with an alternative antihypertensive drug can simplify the diagnostic workup and provide both clinical and histologic improvement.

KW - celiac disease

KW - diarrhea

KW - olmesartan-induced enteropathy

UR - http://www.scopus.com/inward/record.url?scp=85028516102&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85028516102&partnerID=8YFLogxK

U2 - 10.14797/mdcj-12-4-230

DO - 10.14797/mdcj-12-4-230

M3 - Article

C2 - 28289500

AN - SCOPUS:85028516102

VL - 12

SP - 230

EP - 232

JO - Methodist DeBakey cardiovascular journal

JF - Methodist DeBakey cardiovascular journal

SN - 1947-6094

IS - 4

ER -