Sindrome de Ohtahara

Translated title of the contribution: Ohtahara syndrome

K. Yelin, I. Alfonso, O. Papazian

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Introduction. A literature review using the term Ohtahara syndrome and early infantile epileptic encephalopathy revealed 51 cases. Development. The characteristics of these cases were: 1) early onset of seizures; 2) tonic seizures; 3) poor response to treatment; 4) mental retardation; 5) poor prognosis; 6) burst-suppression EEG pattern; 7) evolution to West syndrome, and 8) multiple causes. These characteristics are non specific. No cause was found in most cases. The onset of seizures was between 7 hours and 86 days of age. The most frequent brain imaging abnormality was diffuse atrophy. ACTH was effective in a few cases and hemispherectomy was successful in one case. Conclusion. We believe that Ohtahara syndrome and early myoclonic encephalopathy are the same entity.

Original languageSpanish
Pages (from-to)340-342
Number of pages3
JournalRevista de Neurologia
Volume29
Issue number4
StatePublished - Aug 16 1999

Fingerprint

Seizures
Hemispherectomy
Infantile Spasms
Brain Diseases
Neuroimaging
Intellectual Disability
Adrenocorticotropic Hormone
Atrophy
Electroencephalography
Therapeutics
Epileptic Encephalopathy, Early Infantile, 3

Keywords

  • Epileptic encephalopathy
  • Neonatal seizures
  • Ohtahara syndrome
  • Suppression-burst

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Yelin, K., Alfonso, I., & Papazian, O. (1999). Sindrome de Ohtahara. Revista de Neurologia, 29(4), 340-342.

Sindrome de Ohtahara. / Yelin, K.; Alfonso, I.; Papazian, O.

In: Revista de Neurologia, Vol. 29, No. 4, 16.08.1999, p. 340-342.

Research output: Contribution to journalArticle

Yelin, K, Alfonso, I & Papazian, O 1999, 'Sindrome de Ohtahara', Revista de Neurologia, vol. 29, no. 4, pp. 340-342.
Yelin K, Alfonso I, Papazian O. Sindrome de Ohtahara. Revista de Neurologia. 1999 Aug 16;29(4):340-342.
Yelin, K. ; Alfonso, I. ; Papazian, O. / Sindrome de Ohtahara. In: Revista de Neurologia. 1999 ; Vol. 29, No. 4. pp. 340-342.
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