Ocular Myasthenia

Mohammed Al-Haidar; Michael G Benatar; Henry J. Kaminski

doi:10.1016/j.ncl.2018.01.003

Ocular Myasthenia

Mohammed Al-Haidar, Michael G Benatar, Henry J. Kaminski

Neurology

Research output: Contribution to journal › Review article › peer-review

14 Scopus citations

Abstract

Ocular myasthenia is a form of myasthenia gravis in which weakness is restricted to the ocular muscles and may produce significant visual disability. Patients present with fluctuating ptosis, diplopia, or a combination of both. Examination may show any type of ocular motility deficit ranging from isolated muscle palsy to complete ophthalmoplegia. Cogan lid twitch, enhanced ptosis, peek sign, and saccadic fatigue are specific examination findings that support the clinical diagnosis of myasthenia gravis. Confirmation of the diagnosis is challenging with autoantibody serology, and repetitive nerve stimulation studies are often negative.

Original language	English (US)
Pages (from-to)	241-251
Number of pages	11
Journal	Neurologic Clinics
Volume	36
Issue number	2
DOIs	https://doi.org/10.1016/j.ncl.2018.01.003
State	Published - May 1 2018

Keywords

Acetylcholine receptor
Double vision
Extraocular muscle
Myasthenia gravis
Ocular myasthenia
Prednisone
Ptosis

ASJC Scopus subject areas

Clinical Neurology

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abstract = "Ocular myasthenia is a form of myasthenia gravis in which weakness is restricted to the ocular muscles and may produce significant visual disability. Patients present with fluctuating ptosis, diplopia, or a combination of both. Examination may show any type of ocular motility deficit ranging from isolated muscle palsy to complete ophthalmoplegia. Cogan lid twitch, enhanced ptosis, peek sign, and saccadic fatigue are specific examination findings that support the clinical diagnosis of myasthenia gravis. Confirmation of the diagnosis is challenging with autoantibody serology, and repetitive nerve stimulation studies are often negative.",

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AU - Benatar, Michael G

AU - Kaminski, Henry J.

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AB - Ocular myasthenia is a form of myasthenia gravis in which weakness is restricted to the ocular muscles and may produce significant visual disability. Patients present with fluctuating ptosis, diplopia, or a combination of both. Examination may show any type of ocular motility deficit ranging from isolated muscle palsy to complete ophthalmoplegia. Cogan lid twitch, enhanced ptosis, peek sign, and saccadic fatigue are specific examination findings that support the clinical diagnosis of myasthenia gravis. Confirmation of the diagnosis is challenging with autoantibody serology, and repetitive nerve stimulation studies are often negative.

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KW - Extraocular muscle

KW - Myasthenia gravis

KW - Ocular myasthenia

KW - Prednisone

KW - Ptosis

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Ocular Myasthenia

Abstract

Keywords

ASJC Scopus subject areas

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