Ocular Myasthenia

Mohammed Al-Haidar, Michael G Benatar, Henry J. Kaminski

Research output: Contribution to journalReview article

6 Citations (Scopus)

Abstract

Ocular myasthenia is a form of myasthenia gravis in which weakness is restricted to the ocular muscles and may produce significant visual disability. Patients present with fluctuating ptosis, diplopia, or a combination of both. Examination may show any type of ocular motility deficit ranging from isolated muscle palsy to complete ophthalmoplegia. Cogan lid twitch, enhanced ptosis, peek sign, and saccadic fatigue are specific examination findings that support the clinical diagnosis of myasthenia gravis. Confirmation of the diagnosis is challenging with autoantibody serology, and repetitive nerve stimulation studies are often negative.

Original languageEnglish (US)
Pages (from-to)241-251
Number of pages11
JournalNeurologic Clinics
Volume36
Issue number2
DOIs
StatePublished - May 1 2018

Fingerprint

Myasthenia Gravis
Ophthalmoplegia
Muscles
Diplopia
Serology
Paralysis
Autoantibodies
Fatigue

Keywords

  • Acetylcholine receptor
  • Double vision
  • Extraocular muscle
  • Myasthenia gravis
  • Ocular myasthenia
  • Prednisone
  • Ptosis

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Ocular Myasthenia. / Al-Haidar, Mohammed; Benatar, Michael G; Kaminski, Henry J.

In: Neurologic Clinics, Vol. 36, No. 2, 01.05.2018, p. 241-251.

Research output: Contribution to journalReview article

Al-Haidar, M, Benatar, MG & Kaminski, HJ 2018, 'Ocular Myasthenia', Neurologic Clinics, vol. 36, no. 2, pp. 241-251. https://doi.org/10.1016/j.ncl.2018.01.003
Al-Haidar, Mohammed ; Benatar, Michael G ; Kaminski, Henry J. / Ocular Myasthenia. In: Neurologic Clinics. 2018 ; Vol. 36, No. 2. pp. 241-251.
@article{8a00da7f4ea24cebb21ff833760641d2,
title = "Ocular Myasthenia",
abstract = "Ocular myasthenia is a form of myasthenia gravis in which weakness is restricted to the ocular muscles and may produce significant visual disability. Patients present with fluctuating ptosis, diplopia, or a combination of both. Examination may show any type of ocular motility deficit ranging from isolated muscle palsy to complete ophthalmoplegia. Cogan lid twitch, enhanced ptosis, peek sign, and saccadic fatigue are specific examination findings that support the clinical diagnosis of myasthenia gravis. Confirmation of the diagnosis is challenging with autoantibody serology, and repetitive nerve stimulation studies are often negative.",
keywords = "Acetylcholine receptor, Double vision, Extraocular muscle, Myasthenia gravis, Ocular myasthenia, Prednisone, Ptosis",
author = "Mohammed Al-Haidar and Benatar, {Michael G} and Kaminski, {Henry J.}",
year = "2018",
month = "5",
day = "1",
doi = "10.1016/j.ncl.2018.01.003",
language = "English (US)",
volume = "36",
pages = "241--251",
journal = "Neurologic Clinics",
issn = "0733-8619",
publisher = "W.B. Saunders Ltd",
number = "2",

}

TY - JOUR

T1 - Ocular Myasthenia

AU - Al-Haidar, Mohammed

AU - Benatar, Michael G

AU - Kaminski, Henry J.

PY - 2018/5/1

Y1 - 2018/5/1

N2 - Ocular myasthenia is a form of myasthenia gravis in which weakness is restricted to the ocular muscles and may produce significant visual disability. Patients present with fluctuating ptosis, diplopia, or a combination of both. Examination may show any type of ocular motility deficit ranging from isolated muscle palsy to complete ophthalmoplegia. Cogan lid twitch, enhanced ptosis, peek sign, and saccadic fatigue are specific examination findings that support the clinical diagnosis of myasthenia gravis. Confirmation of the diagnosis is challenging with autoantibody serology, and repetitive nerve stimulation studies are often negative.

AB - Ocular myasthenia is a form of myasthenia gravis in which weakness is restricted to the ocular muscles and may produce significant visual disability. Patients present with fluctuating ptosis, diplopia, or a combination of both. Examination may show any type of ocular motility deficit ranging from isolated muscle palsy to complete ophthalmoplegia. Cogan lid twitch, enhanced ptosis, peek sign, and saccadic fatigue are specific examination findings that support the clinical diagnosis of myasthenia gravis. Confirmation of the diagnosis is challenging with autoantibody serology, and repetitive nerve stimulation studies are often negative.

KW - Acetylcholine receptor

KW - Double vision

KW - Extraocular muscle

KW - Myasthenia gravis

KW - Ocular myasthenia

KW - Prednisone

KW - Ptosis

UR - http://www.scopus.com/inward/record.url?scp=85045210228&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85045210228&partnerID=8YFLogxK

U2 - 10.1016/j.ncl.2018.01.003

DO - 10.1016/j.ncl.2018.01.003

M3 - Review article

C2 - 29655447

AN - SCOPUS:85045210228

VL - 36

SP - 241

EP - 251

JO - Neurologic Clinics

JF - Neurologic Clinics

SN - 0733-8619

IS - 2

ER -