Ocular Manifestations of ANCA-associated Vasculitis

Anup A. Kubal, Victor L Perez Quinones

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

The antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides-Wegener's granulomatosis, microscopic polyangiitis, and Churg-Strauss syndrome-can present with various ophthalmic manifestations. In a subset of patients, these findings may be the earliest indicators of systemic disease. Orbital and anterior segment findings are most common, whereas posterior segment complications such as retinal vasculitis and optic neuropathy occur much less frequently. This article describes the distinguishing features of associated ophthalmic disease, focusing on the manifestations clinicians are most likely to encounter and those with the most significant ocular morbidity. Although the ANCA-associated vasculitides require systemic workup and treatment, this article discusses diagnostic and therapeutic modalities often used concurrently for ophthalmic disease.

Original languageEnglish
Pages (from-to)573-586
Number of pages14
JournalRheumatic Disease Clinics of North America
Volume36
Issue number3
DOIs
StatePublished - Aug 1 2010

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Eye Manifestations
Antineutrophil Cytoplasmic Antibodies
Eye Diseases
Vasculitis
Retinal Vasculitis
Microscopic Polyangiitis
Churg-Strauss Syndrome
Systemic Vasculitis
Optic Nerve Diseases
Granulomatosis with Polyangiitis
Morbidity
Therapeutics

Keywords

  • Antineutrophil cytoplasmic antibody
  • Churg-Strauss syndrome
  • Microscopic polyangiitis
  • Wegener's granulomatosis

ASJC Scopus subject areas

  • Rheumatology

Cite this

Ocular Manifestations of ANCA-associated Vasculitis. / Kubal, Anup A.; Perez Quinones, Victor L.

In: Rheumatic Disease Clinics of North America, Vol. 36, No. 3, 01.08.2010, p. 573-586.

Research output: Contribution to journalArticle

Kubal, Anup A. ; Perez Quinones, Victor L. / Ocular Manifestations of ANCA-associated Vasculitis. In: Rheumatic Disease Clinics of North America. 2010 ; Vol. 36, No. 3. pp. 573-586.
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