Ocular Manifestations in Pediatric Patients with Acquired Immunodeficiency Syndrome

Patrick J. Dennehy, Roberto Warman, John T. Flynn, Gwendolyn B. Scott, Mary T. Mastrucci

Research output: Contribution to journalArticlepeer-review

49 Scopus citations


Forty pediatric patients seropositive for human immunodeficiency virus antibody and conforming to Centers for Disease Control, Atlanta, Ga, case definition of acquired immunodeficiency syndrome underwent ophthalmic examinations to evaluate prospectively the incidence, type, and natural history of ocular involvement in pediatric acquired immunodeficiency syndrome. A total of 87 examinations were performed on the patient population throughout the course of the study. Twenty percent had ocular findings, including two cases of cytomegalovirus retinitis, one case of isolated retinal cottonwool spots, one case of toxoplasmosis retinochoroiditis, and three cases of external infections of adnexal structures. One patient had unusual peripheral retinal findings. The incidence of ocular manifestations in pediatric acquired immunodeficiency syndrome is considerably less than reported in several adult series. However, we recommend ophthalmic screening in all pediatric patients with acquired immunodeficiency syndrome with encephalopathy or disseminated opportunistic infections, or when symptoms suggest ophthalmic involvement.

Original languageEnglish (US)
Pages (from-to)978-982
Number of pages5
JournalArchives of ophthalmology
Issue number7
StatePublished - Jul 1989

ASJC Scopus subject areas

  • Ophthalmology


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