Ocular effects of exposure to industrial chemicals: Clinical management and proteomic approaches to damage assessment

Sanjoy K. Bhattacharya, Gregory G. Hom, Christopher Fernandez, Louis G. Hom

Research output: Contribution to journalReview article

10 Scopus citations

Abstract

Industrial chemicals in a variety of applications are often found in highly populated areas and their presence carries risks. The threat of serious consequences from inadvertent or intentional events involving hazardous chemicals is a possibility. Extremism and/or other illicit activities pose environmental threats from chemical exposures. We present here a review of the threat of ocular injury in small-and large-scale chemical releases and discuss mechanisms of damage and repair to the eyes. The emerging field of proteomics has been described in relation to its potential role in the assessment of ocular changes following chemical exposures and management of ocular trauma.

Original languageEnglish (US)
Pages (from-to)203-225
Number of pages23
JournalCutaneous and Ocular Toxicology
Volume26
Issue number3
DOIs
StatePublished - Jul 1 2007

Keywords

  • Chemical exposure
  • Eye injury
  • Mass casualties
  • Proteomics

ASJC Scopus subject areas

  • Health, Toxicology and Mutagenesis
  • Ophthalmology
  • Toxicology

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