Ocular Decompression Devices: Liquid Mercury Balloon vs the Tungsten Powder Balloon

Steven Gayer, David Denham, Karim Alarakhia, Andres Bernal, Gabriel Cardenas, Robert Duncan, Jean Marie Parel

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Purpose: To determine if an intraocular pressure (IOP)-reducing device containing tungsten powder decreases pressure comparably to the traditional mercury-containing apparatus. Design: Prospective randomized, single-blind, controlled, phase I equivalence study. Method: At a tertiary care center, both eyes of 24 volunteers with normal IOP were treated with an ocular compression device containing either liquid mercury or tungsten powder. The IOP was measured at baseline and after 10 minutes of ocular compression. Results: The mean reduction in IOP was 3.6 mm Hg ± 2.0 with the mercury-containing device and 4.4 mm Hg ± 2.1 with the tungsten-filled apparatus. An equivalence study analysis using a paired t-test and a sequential analysis protocol did not demonstrate a statistically significant difference between the IOP-lowering effects of the two devices. Conclusions: The IOP-lowering effect produced by a tungsten powder-filled balloon ocular decompression device compared with a traditional mercury-containing device was not statistically different.

Original languageEnglish (US)
Pages (from-to)500-501
Number of pages2
JournalAmerican journal of ophthalmology
Issue number3
StatePublished - Sep 2006

ASJC Scopus subject areas

  • Ophthalmology


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