Ocular adnexal lymphoma: No evidence for bacterial DNA associated with lymphoma pathogenesis

Julie M. Matthews, Lilliana I. Moreno, Jeremy Dennis, Gerald E. Byrne, Phillip Ruiz, Sander Dubovy, Izidore Lossos

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

Ocular Adnexal Lymphomas (OALs) are the most common tumors of the eye, the majority being extranodal mucosa-associated lymphoid tissue (MALT) lymphomas. Association with Chlamydia psittaci was described in some geographic areas. OAL response to antibiotic therapy was reported in cases not harboring Chlamydia psittaci DNA, suggesting that other bacterial infection might be implicated in the pathogenesis. We examined 49 MALT OALs for bacterial DNA using two distinct polymerase chain reaction techniques based on universal bacterial primers. No bacterial DNA that could be implicated in OAL pathogenesis was detected, suggesting that bacterial infection is not associated with OAL in South Florida.

Original languageEnglish
Pages (from-to)246-249
Number of pages4
JournalBritish Journal of Haematology
Volume142
Issue number2
DOIs
StatePublished - Jul 1 2008

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Keywords

  • Chlamydia
  • MALT
  • Ocular adnexal lymphoma

ASJC Scopus subject areas

  • Hematology

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