El trastorno obsesivo-compulsivo y sus trastornos relacionados: Una reevaluación de los conceptos del espectro obsesivocompulsivo

Translated title of the contribution: Obsessive-compulsive disorder and its related disorders: A reappraisal of obsessive-compulsive spectrum concepts

Dennis L. Murphy, Kiara R. Timpano, Michael G. Wheaton, Benjamin D. Greenberg, Euripedes C. Miguel

Research output: Contribution to journalArticle

47 Scopus citations

Abstract

Obsessive-compulsive disorder (OCD) is a clinical syndrome whose hallmarks are excessive, anxiety-evoking thoughts and compulsive behaviors that are generally recognized as unreasonable, but which cause significant distress and impairment. When these are the exclusive symptoms, they constitute uncomplicated OCD. OCD may also occur in the context of other neuropsychiatric disorders, most commonly other anxiety and mood disorders. The question remains as to whether these combinations of disorders should be regarded as independent, cooccurring disorders or as different manifestations of an incompletely understood constellation of OCD spectrum disorders with a common etiology. Additional considerations are given here to two potential etiology-based subgroups: (i) an environmentally based group in which OCD occurs following apparent causal events such as streptococcal infections, brain injury, or atypical neuroleptic treatment; and (ii) a genomically based group in which OCD is related to chromosomal anomalies or specific genes. Considering the status of current research, the concept of OCD and OCD-related spectrum conditions seems fluid in 2010, and in need of ongoing reappraisal.

Translated title of the contributionObsessive-compulsive disorder and its related disorders: A reappraisal of obsessive-compulsive spectrum concepts
Original languageSpanish
Pages (from-to)131-148
Number of pages18
JournalDialogues in clinical neuroscience
Volume12
Issue number2
StatePublished - Dec 2 2010
Externally publishedYes

Keywords

  • Anxiety
  • Comorbid disorder
  • Compulsion
  • Compulsive hoarding
  • Depression
  • Environmental influence
  • Genetics
  • Genomics
  • Obsession
  • Tourette syndrome

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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