TY - JOUR
T1 - Obscure gastrointestinal bleeding
T2 - Diagnostic and therapeutic approach
AU - Concha, Ronald
AU - Amaro, Rafael
AU - Barkin, Jamie S.
PY - 2007/3/1
Y1 - 2007/3/1
N2 - Obscure gastrointestinal bleeding (OGIB) is defined as an intermittent or continuous loss of blood in which the source has not been identified after upper endoscopy and colonoscopy. It constitutes a diagnostic and therapeutic challenge for the general internist and the gastroenterologist. This article provides an overview of the etiology, clinical presentation, and diagnostic modalities of OGIB including push enteroscopy, double balloon enteroscopy, wireless capsule endoscopy, enteroclysis, angiography, bleeding scanning with labeled red blood cells, and surgery with intraoperative enteroscopy. Therapeutic modalities including iron replacement, combined hormones, octreotide acetate, therapeutic endoscopy, and surgery are also discussed. In addition, a rational approach to patients with OGIB according to the clinical presentation is presented herein.
AB - Obscure gastrointestinal bleeding (OGIB) is defined as an intermittent or continuous loss of blood in which the source has not been identified after upper endoscopy and colonoscopy. It constitutes a diagnostic and therapeutic challenge for the general internist and the gastroenterologist. This article provides an overview of the etiology, clinical presentation, and diagnostic modalities of OGIB including push enteroscopy, double balloon enteroscopy, wireless capsule endoscopy, enteroclysis, angiography, bleeding scanning with labeled red blood cells, and surgery with intraoperative enteroscopy. Therapeutic modalities including iron replacement, combined hormones, octreotide acetate, therapeutic endoscopy, and surgery are also discussed. In addition, a rational approach to patients with OGIB according to the clinical presentation is presented herein.
KW - Angiodysplasias
KW - Capsule endoscopy
KW - Double balloon enteroscopy
KW - Enteroscopy
KW - Gastrointestinal hemorrhage
KW - Obscure bleeding
KW - Occult bleeding
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U2 - 10.1097/01.mcg.0000225616.79223.75
DO - 10.1097/01.mcg.0000225616.79223.75
M3 - Review article
C2 - 17426461
AN - SCOPUS:33847387597
VL - 41
SP - 242
EP - 251
JO - Journal of Clinical Gastroenterology
JF - Journal of Clinical Gastroenterology
SN - 0192-0790
IS - 3
ER -