OARSI Clinical Trials Recommendations: Knee imaging in clinical trials inosteoarthritis

D. J. Hunter, Roy D Altman, F. Cicuttini, M. D. Crema, J. Duryea, F. Eckstein, A. Guermazi, R. Kijowski, T. M. Link, J. Martel-Pelletier, C. G. Miller, T. J. Mosher, R. E. Ochoa-Albíztegui, J. P. Pelletier, C. Peterfy, J. P. Raynauld, F. W. Roemer, S. M. Totterman, G. E. Gold

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Significant advances have occurred in our understanding of the pathogenesis of knee osteoarthritis (OA) and some recent trials have demonstrated the potential for modification of the disease course. The purpose of this expert opinion, consensus driven exercise is to provide detail on how one might use and apply knee imaging in knee OA trials. It includes information on acquisition methods/techniques (including guidance on positioning for radiography, sequence/protocol recommendations/hardware for magnetic resonance imaging (MRI)); commonly encountered problems (including positioning, hardware and coil failures, sequences artifacts); quality assurance (QA)/control procedures; measurement methods; measurement performance (reliability, responsiveness, validity); recommendations for trials; and research recommendations.

Original languageEnglish (US)
Pages (from-to)698-715
Number of pages18
JournalOsteoarthritis and Cartilage
Volume23
Issue number5
DOIs
StatePublished - 2015
Externally publishedYes

Fingerprint

Knee
Knee Osteoarthritis
Clinical Trials
Hardware
Imaging techniques
Radiography
Magnetic resonance
Quality assurance
Expert Testimony
Reproducibility of Results
Quality Control
Artifacts
Magnetic Resonance Imaging
Research

Keywords

  • Clinical trial recommendations
  • Imaging
  • Knee osteoarthritis

ASJC Scopus subject areas

  • Biomedical Engineering
  • Orthopedics and Sports Medicine
  • Rheumatology

Cite this

Hunter, D. J., Altman, R. D., Cicuttini, F., Crema, M. D., Duryea, J., Eckstein, F., ... Gold, G. E. (2015). OARSI Clinical Trials Recommendations: Knee imaging in clinical trials inosteoarthritis. Osteoarthritis and Cartilage, 23(5), 698-715. https://doi.org/10.1016/j.joca.2015.03.012

OARSI Clinical Trials Recommendations : Knee imaging in clinical trials inosteoarthritis. / Hunter, D. J.; Altman, Roy D; Cicuttini, F.; Crema, M. D.; Duryea, J.; Eckstein, F.; Guermazi, A.; Kijowski, R.; Link, T. M.; Martel-Pelletier, J.; Miller, C. G.; Mosher, T. J.; Ochoa-Albíztegui, R. E.; Pelletier, J. P.; Peterfy, C.; Raynauld, J. P.; Roemer, F. W.; Totterman, S. M.; Gold, G. E.

In: Osteoarthritis and Cartilage, Vol. 23, No. 5, 2015, p. 698-715.

Research output: Contribution to journalArticle

Hunter, DJ, Altman, RD, Cicuttini, F, Crema, MD, Duryea, J, Eckstein, F, Guermazi, A, Kijowski, R, Link, TM, Martel-Pelletier, J, Miller, CG, Mosher, TJ, Ochoa-Albíztegui, RE, Pelletier, JP, Peterfy, C, Raynauld, JP, Roemer, FW, Totterman, SM & Gold, GE 2015, 'OARSI Clinical Trials Recommendations: Knee imaging in clinical trials inosteoarthritis', Osteoarthritis and Cartilage, vol. 23, no. 5, pp. 698-715. https://doi.org/10.1016/j.joca.2015.03.012
Hunter, D. J. ; Altman, Roy D ; Cicuttini, F. ; Crema, M. D. ; Duryea, J. ; Eckstein, F. ; Guermazi, A. ; Kijowski, R. ; Link, T. M. ; Martel-Pelletier, J. ; Miller, C. G. ; Mosher, T. J. ; Ochoa-Albíztegui, R. E. ; Pelletier, J. P. ; Peterfy, C. ; Raynauld, J. P. ; Roemer, F. W. ; Totterman, S. M. ; Gold, G. E. / OARSI Clinical Trials Recommendations : Knee imaging in clinical trials inosteoarthritis. In: Osteoarthritis and Cartilage. 2015 ; Vol. 23, No. 5. pp. 698-715.
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