TY - JOUR
T1 - Nutritional Supplements for Age-Related Macular Degeneration
AU - Gregori, Ninel Z.
AU - Goldhardt, Raquel
N1 - Publisher Copyright:
© 2015, Springer Science+Business Media New York (outside the USA).
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2015/3/1
Y1 - 2015/3/1
N2 - The Age-Related Eye Disease Study (AREDS) and The Age-Related Eye Disease Study 2, are the only large-scale, long-term, randomized controlled trials to demonstrate a role of nutritional supplements in reducing risk of progression to advanced forms of age-related macular degeneration (AMD). This review summarizes the study design, main results, and implications of these trials in the clinical care of nonexudative AMD patients. In addition, it discusses other recent prospective studies focusing on efficacy of nutritional supplementation for prevention or slowing progression of AMD as well as briefly discusses possible effect of genotypes on response to AREDS supplementation.
AB - The Age-Related Eye Disease Study (AREDS) and The Age-Related Eye Disease Study 2, are the only large-scale, long-term, randomized controlled trials to demonstrate a role of nutritional supplements in reducing risk of progression to advanced forms of age-related macular degeneration (AMD). This review summarizes the study design, main results, and implications of these trials in the clinical care of nonexudative AMD patients. In addition, it discusses other recent prospective studies focusing on efficacy of nutritional supplementation for prevention or slowing progression of AMD as well as briefly discusses possible effect of genotypes on response to AREDS supplementation.
KW - Age-Related Eye Disease Study
KW - Age-related macular degeneration
KW - Nutritional supplements
KW - Vitamins
UR - http://www.scopus.com/inward/record.url?scp=85027024507&partnerID=8YFLogxK
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U2 - 10.1007/s40135-014-0059-z
DO - 10.1007/s40135-014-0059-z
M3 - Article
AN - SCOPUS:85027024507
VL - 3
SP - 34
EP - 39
JO - Current Ophthalmology Reports
JF - Current Ophthalmology Reports
SN - 2167-4868
IS - 1
ER -