Nucleotide sequence analysis of the inversion termini located within IS3 elements α3β3 and β5α5 of Escherichia coli K-12

D. Ajdic, G. Jovanovic, V. Glisin, J. Hejna, D. J. Savic

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This paper presents the first detailed structural analysis of termini of an inversion mediated by recombination between Escherichia coli native IS elements. The complete nucleotide sequence of the inversion termini in the lactose region of Escherichia coli K-12 confirms our previous suggestion that the inversion occurred by homologous recombination between α3β3 and β5α5 IS3 elements (D.J. Savic, J. Bacteriol. 140:311-319, 1979; D.J. Savic, S. Romac, and S.D. Ehrlich, J. Bacteriol. 155:943-946, 1983). The data show a slight structural divergence of α3β3 and β5α5 elements, but they do not reveal new sequences within recomhined IS3 elements that could influence the expression of nearby genes.

Original languageEnglish (US)
Pages (from-to)906-909
Number of pages4
JournalJournal of bacteriology
Issue number2
StatePublished - 1991
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology


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