Novel 7-alkyl methylenedioxy-camptothecin derivatives exhibit increased cytotoxicity and induce persistent cleavable complexes both with purified mammalian topoisomerase I and in human colon carcinoma SW620 cells

Monica Valenti, Wilberto Nieves-Neira, Glenda Kohlhagen, Kurt W. Kohn, Monroe E. Wall, Mansukh C. Wani, Yves Pommier

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35 Scopus citations

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Medicine & Life Sciences