Nosocomial acute-onset postoperative endophthalmitis survey: A 10-year review of incidence and outcomes

Thomas M. Aaberg, Harry W Flynn, Joyce Schiffman, Jean Newton

Research output: Contribution to journalArticle

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Abstract

Objective: The purpose of the study was to evaluate the incidence of acute-onset (within 6 weeks after surgery) postoperative endophthalmitis and to assess the visual acuity outcomes after treatment over a 10-year period at one institution. Patients and Methods: This retrospective study reviews all surgical cases performed between January 1, 1984 and December 30, 1994 at the Anne Bates Leach Eye Hospital, Bascom Palmer Eye Institute, University of Miami Medical Center, for the occurrence of nosocomial acute-onset postoperative endophthalmitis. Results: The overall 10-year incidence of acute-onset postoperative endophthalmitis after intraocular surgery was 0.093% (54/58, 123). The incidences of culture-proven acute-onset postoperative endophthalmitis by surgical category were as follows: cataract surgery with or without intraocular lens (IOL) (0.082%, 34/41, 654), pans plana vitrectomy (PPV) (0.046%, 3/6557), penetrating keratoplasty (0.178%, 5/2805), secondary IOL placement (0.366%, 5/1367), glaucoma surgeries (0.124%, 4/3233), combined trabeculectomy and cataract surgery (0.114%, 2/1743), and combined penetrating keratoplasty and cataract surgery (0.194%, 1/515). The median visual acuity after endophthalmitis treatment was 20/200. The median visual acuities after endophthalmitis treatment by procedure were as follows: cataract surgery with or without IOL (20/133), PPV (no light perception), penetrating keratoplasty (2/200), secondary IOL implantation (20/40), glaucoma surgery (20/80), and combined trabeculectomy and cataract surgery with or without IOL (20/150). Conclusions: The overall incidence of endophthalmitis after intraocular surgery was 0.093%. The incidence of endophthalmitis was higher after secondary IOL implantation than after cataract extraction (P = 0.008, Fisher's exact test). After treatment, the visual acuity outcomes were worse in the patients who developed endophthalmitis after PPV than after cataract extraction, glaucoma procedures, or secondary IOL implantation (P < 0.05, analysis of variance, Duncan's multiple range test). Acuity outcomes after treatment of endophthalmitis were better among the patients with secondary IOL implantation than after penetrating keratoplasty or PPV (P < 0.05, analysis of variance, Duncan's multiple range test). The results of this 10-year review from a large teaching center may serve as a source of comparison for other centers and future studies.

Original languageEnglish
Pages (from-to)1004-1010
Number of pages7
JournalOphthalmology
Volume105
Issue number6
DOIs
StatePublished - Jun 1 1998

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Endophthalmitis
antineoplaston A10
Incidence
Penetrating Keratoplasty
Intraocular Lens Implantation
Temazepam
Cataract
Intraocular Lenses
Vitrectomy
Visual Acuity
Glaucoma
Trabeculectomy
Cataract Extraction
Analysis of Variance
Surveys and Questionnaires
Teaching
Therapeutics
Retrospective Studies
Light

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Nosocomial acute-onset postoperative endophthalmitis survey : A 10-year review of incidence and outcomes. / Aaberg, Thomas M.; Flynn, Harry W; Schiffman, Joyce; Newton, Jean.

In: Ophthalmology, Vol. 105, No. 6, 01.06.1998, p. 1004-1010.

Research output: Contribution to journalArticle

Aaberg, Thomas M. ; Flynn, Harry W ; Schiffman, Joyce ; Newton, Jean. / Nosocomial acute-onset postoperative endophthalmitis survey : A 10-year review of incidence and outcomes. In: Ophthalmology. 1998 ; Vol. 105, No. 6. pp. 1004-1010.
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abstract = "Objective: The purpose of the study was to evaluate the incidence of acute-onset (within 6 weeks after surgery) postoperative endophthalmitis and to assess the visual acuity outcomes after treatment over a 10-year period at one institution. Patients and Methods: This retrospective study reviews all surgical cases performed between January 1, 1984 and December 30, 1994 at the Anne Bates Leach Eye Hospital, Bascom Palmer Eye Institute, University of Miami Medical Center, for the occurrence of nosocomial acute-onset postoperative endophthalmitis. Results: The overall 10-year incidence of acute-onset postoperative endophthalmitis after intraocular surgery was 0.093{\%} (54/58, 123). The incidences of culture-proven acute-onset postoperative endophthalmitis by surgical category were as follows: cataract surgery with or without intraocular lens (IOL) (0.082{\%}, 34/41, 654), pans plana vitrectomy (PPV) (0.046{\%}, 3/6557), penetrating keratoplasty (0.178{\%}, 5/2805), secondary IOL placement (0.366{\%}, 5/1367), glaucoma surgeries (0.124{\%}, 4/3233), combined trabeculectomy and cataract surgery (0.114{\%}, 2/1743), and combined penetrating keratoplasty and cataract surgery (0.194{\%}, 1/515). The median visual acuity after endophthalmitis treatment was 20/200. The median visual acuities after endophthalmitis treatment by procedure were as follows: cataract surgery with or without IOL (20/133), PPV (no light perception), penetrating keratoplasty (2/200), secondary IOL implantation (20/40), glaucoma surgery (20/80), and combined trabeculectomy and cataract surgery with or without IOL (20/150). Conclusions: The overall incidence of endophthalmitis after intraocular surgery was 0.093{\%}. The incidence of endophthalmitis was higher after secondary IOL implantation than after cataract extraction (P = 0.008, Fisher's exact test). After treatment, the visual acuity outcomes were worse in the patients who developed endophthalmitis after PPV than after cataract extraction, glaucoma procedures, or secondary IOL implantation (P < 0.05, analysis of variance, Duncan's multiple range test). Acuity outcomes after treatment of endophthalmitis were better among the patients with secondary IOL implantation than after penetrating keratoplasty or PPV (P < 0.05, analysis of variance, Duncan's multiple range test). The results of this 10-year review from a large teaching center may serve as a source of comparison for other centers and future studies.",
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