North Carolina macular dystrophy: Exclusion map using RFLPs and microsatellites

Kent W. Small, James L. Weber, Wu Yen Hung, Jeffery M Vance, Allen Roses, Margaret A Pericak-Vance

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The autosomal dominant macular dystrophies are a confusing group of poorly understood diseases. Linkage studies will greatly aid our classification of these disorders and hopefully provide insight into central retinal function and dysfunction such as occurs in age-related macular degeneration. North Carolina macular dystrophy is one such disease that has been amenable to linkage analysis because of the large pedigree size. Seventy-six polymorphic markers have been tested for linkage and exclusion data are presented.

Original languageEnglish
Pages (from-to)763-766
Number of pages4
JournalGenomics
Volume11
Issue number3
DOIs
StatePublished - Jan 1 1991
Externally publishedYes

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Macular Degeneration
Restriction Fragment Length Polymorphisms
Microsatellite Repeats
Information Storage and Retrieval
Pedigree
Macular dystrophy, retinal, 1, North Carolina type

ASJC Scopus subject areas

  • Genetics

Cite this

North Carolina macular dystrophy : Exclusion map using RFLPs and microsatellites. / Small, Kent W.; Weber, James L.; Hung, Wu Yen; Vance, Jeffery M; Roses, Allen; Pericak-Vance, Margaret A.

In: Genomics, Vol. 11, No. 3, 01.01.1991, p. 763-766.

Research output: Contribution to journalArticle

Small, Kent W. ; Weber, James L. ; Hung, Wu Yen ; Vance, Jeffery M ; Roses, Allen ; Pericak-Vance, Margaret A. / North Carolina macular dystrophy : Exclusion map using RFLPs and microsatellites. In: Genomics. 1991 ; Vol. 11, No. 3. pp. 763-766.
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