“Normal pressure” pseudotumor cerebri

Jeffrey P. Green, Nancy J. Newman, Zachary N. Stowe, Charles Nemeroff

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


We present a case report of a patient with clinical features suggestive of pseudotumor cerebri (PTC), without a documented elevated measurement of intracranial pressure (ICP). Chart review was done of one patient’s clinical course over a 28-month period. The patient was treated for PTC even though she never had a documented elevated ICP. Her signs and symptoms, including headache, disc edema, and visual field loss, all showed improvement with standard PTC therapy, which ultimately included optic nerve sheath fenestration (ONSF). Her presenting symptoms of clinical depression were also relieved with this treatment. PTC may present without an elevated ICP as defined by current standards. Some patients may be more susceptible to lower levels of ICP and develop this syndrome, and it may be responsive to standard PTC therapy. Further investigation may warrant that clinical depression be included as another minor symptom of PTC.

Original languageEnglish (US)
Pages (from-to)241-246
Number of pages6
JournalJournal of Neuro-Ophthalmology
Issue number4
StatePublished - 1996
Externally publishedYes


  • Depression
  • Intracranial pressure
  • Optic nerve sheath fenestration
  • Pseudotumor cerebri

ASJC Scopus subject areas

  • Ophthalmology
  • Clinical Neurology


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