Nonpenetrating keratoprosthesis

Bernard M.D. Duchesne, Jean Marie Parel, Sabine Gautier, Fabrice Manns, H. Kondo, Emmanuel M.D. Lacombe, Jean Marc M.D. Legeais, E. Alfonso

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations


The concept and invention of the non-penetrating keratoprosthesis were described in 1991 by Legeais, Parel, Villain, Tseng and Lacombe. The main advantage of the non-penetrating keratoprosthesis is that Descemet's membrane and the endothelium are kept in place. Therefore, the risk of endophthalmitis may be reduced, and anterior chamber effraction and pressure modification may be avoided. The prosthesis was designed with a 7 mm diameter optic and a 10 mm diameter skirt made of expanded polytetrafluoroethylene (ePTFE). A flange in teflon was used to ensure biointegration of the prosthesis. We carried out 3 preliminary studies in Eye-Bank eyes and rabbits, in order to assess surgical feasibility, Descemet membrane strength, and biocompatibility of different types of polymers. We are also currently conducting a study on rabbits.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsJean-Marie Parel, Karen M. Joos, Pascal O. Rol
Number of pages3
StatePublished - 1996
EventOphthalmic Technologies VI - San Jose, CA, USA
Duration: Jan 27 1996Jan 28 1996

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering


OtherOphthalmic Technologies VI
CitySan Jose, CA, USA

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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