Nonparametric cluster analysis of autoradiographic images

K. Yin, Weizhao Zhao, T. Y. Young, Myron Ginsberg

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper describes a novel non-parametric statistical method based on cluster analysis for localizing significant differences in autoradiographic image data sets under two conditions. By thresholding cluster-size rather than pixel-values to reject false positives, this approach enhances statistical power. This test makes no assumption as to probability distribution or other properties of the statistical parametric map (SPM). The computational burden entailed by Monte-Carlo method is also greatly reduced by a randomization method.

Original languageEnglish
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Place of PublicationPiscataway, NJ, United States
PublisherIEEE
Volume2
ISBN (Print)0780356756
StatePublished - Dec 1 1999
EventProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) - Atlanta, GA, USA
Duration: Oct 13 1999Oct 16 1999

Other

OtherProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
CityAtlanta, GA, USA
Period10/13/9910/16/99

Fingerprint

Cluster analysis
Probability distributions
Statistical methods
Monte Carlo methods
Pixels

ASJC Scopus subject areas

  • Bioengineering

Cite this

Yin, K., Zhao, W., Young, T. Y., & Ginsberg, M. (1999). Nonparametric cluster analysis of autoradiographic images. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 2). Piscataway, NJ, United States: IEEE.

Nonparametric cluster analysis of autoradiographic images. / Yin, K.; Zhao, Weizhao; Young, T. Y.; Ginsberg, Myron.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 2 Piscataway, NJ, United States : IEEE, 1999.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Yin, K, Zhao, W, Young, TY & Ginsberg, M 1999, Nonparametric cluster analysis of autoradiographic images. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. vol. 2, IEEE, Piscataway, NJ, United States, Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS), Atlanta, GA, USA, 10/13/99.
Yin K, Zhao W, Young TY, Ginsberg M. Nonparametric cluster analysis of autoradiographic images. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 2. Piscataway, NJ, United States: IEEE. 1999
Yin, K. ; Zhao, Weizhao ; Young, T. Y. ; Ginsberg, Myron. / Nonparametric cluster analysis of autoradiographic images. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 2 Piscataway, NJ, United States : IEEE, 1999.
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