Noninvasive assessment of cardiovascular reactivity and its significance as an indicator of risk for hypertension

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1 Scopus citations


Cardiovascular reactivity to stressful challenge has become an accepted means of studying the pathophysiology of cardiovascular diseases. Though the generality of associations between cardiovascular reactivity in the laboratory and risk between cardiovascular reactivity and hypertension to confirm the utility of hyperreactivity as a risk factor for future essential hypertension. It has been shown, for example, that a stressor primarily eliciting an increase in total peripheral resistance is appropriate for detecting the relationship between reactivity at a young age and hypertension many years later. Important prerequisites for the validity of the reactivity- hypertension association are the proper selection of psychological stressor as well as the adequate acquisition and processing of physiological parameters for the assessment of reactivity. To compare the different cardiovascular responses evoked by various test challenges and to determine the tored including blood pressure, heart rate, stroke volume, cardiac output, total peripheral resistance, vagal tone. Heather index, and other systolic time interval indices of myocardial contractility. Innovative approaches to instrumentation and signal processing had to be developed and validated to improve reliability, accuracy, and precision of these measurements. The new techniques, especially improved impedance cardiography for the determination of stroke volume and an adaptive filter technique for the estimation of vagal tone, together with refined procedures for the delivery of psychologically stimulating stressors have provided the means of reliable assessment of cardiovascular reactivity and for studies aiming at further confirmation of its significance as an indicator of risk for future hypertension.

Original languageEnglish (US)
Pages (from-to)230-241
Number of pages12
JournalBiomedical Engineering - Applications, Basis and Communications
Issue number4
StatePublished - Aug 25 1997
Externally publishedYes


  • Cardiovascular Reactivity
  • Hypertension
  • Impedance Cardiography
  • Signal Processing

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering


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