Abstract
Acute liver failure (ALF) is an uncommon syndrome with a highly variable and unpredictable clinical course. The initial diagnostic evaluation is typically performed in a non–intensive care unit (ICU) setting, like the emergency department or general hospital ward. Prompt restoration of intravascular volume with intravenous fluids and correction of electrolyte, metabolic, and acid-base disturbances are important initial interventions in the management of ALF and can be safely accomplished in non-ICU settings in many patients. Similarly, therapies such as administration of N-acetylcysteine for acetaminophen-induced ALF and other cause-specific interventions can also be administered in non-ICU settings, thus minimizing delay.
Original language | English (US) |
---|---|
Pages (from-to) | 389-401 |
Number of pages | 13 |
Journal | Clinics in liver disease |
Volume | 22 |
Issue number | 2 |
DOIs | |
State | Published - May 2018 |
Keywords
- Acute liver failure
- Emergency department
- Hospital ward
- Treatment
ASJC Scopus subject areas
- Hepatology