Noncovalent encapsulation of cobaltocenium inside resorcinarene molecular capsules

Ivy Philip, Angel E. Kaifer

Research output: Contribution to journalArticle

49 Scopus citations

Abstract

(Chemical Equation Presented) The encapsulation of cobaltocenium (Cob +) inside hexameric molecular capsules of two different resorcinarenes was investigated in dichloromethane solution. Both 1H NMR spectroscopic and voltammetric experiments clearly reveal that Cob + experiences encapsulation. Diffusion coefficient measurements obtained from PGSE NMR experiments indicate that the molecular capsules exist in dichloromethane solution in the absence of any cations. Bound and free Cob + ions undergo slow exchange on the NMR time scale, but the bound Cob+ ions rotate and/or tumble freely inside the molecular capsules. Under experimental conditions suitable for voltammetry the encapsulation of Cob+ depends on the nature of the supporting electrolyte. Tetraalkylammonium hexafluorophosphate, tetrafluoroborate, and perchlorate supporting electrolytes prevent the encapsulation of Cob+, while tetraalkylammonium chloride and bromide salts allow it. The nature of the tetraalkylammonium cation plays a smaller role in the encapsulation. Finally, the structure of the resorcinarene also factors into the overall stability of the molecular assembly.

Original languageEnglish (US)
Pages (from-to)1558-1564
Number of pages7
JournalJournal of Organic Chemistry
Volume70
Issue number5
DOIs
StatePublished - Mar 4 2005

ASJC Scopus subject areas

  • Organic Chemistry

Fingerprint Dive into the research topics of 'Noncovalent encapsulation of cobaltocenium inside resorcinarene molecular capsules'. Together they form a unique fingerprint.

  • Cite this