Abstract
Background: This study aimed to evaluate the feasibility and accuracy of 16-slice computed tomography (CT) in the assessment of coronary stent patency. CT coronary angiography (CA) has a high degree of accuracy in the assessment of coronary artery disease compared with invasive selective CA. However, its accuracy in the evaluation of stent patency is not well investigated. Methods: We conducted a retrospective observational study of paired CT coronary angiography (CT-CA) and invasive fluoroscopic coronary angiography (FCA) in 37 patients with 47 coronary stents. CT-CA was carried out with an electrocardiogram-gated 16-slice CT (LightSpeed-16, General Electric (GE), WI, USA). Two CT reporters, blinded to the FCA findings, assessed CT images for stent patency. A cardiologist blinded to CT findings reported FCA. FCA was regarded as the reference standard. Results: A CT-CA could assess 45 of 47 coronary stents (96%). Non-assessable stents on CT-CA were due to motion artefacts and stent-blooming effects. Of those 45 assessable stents, CT-CA correctly identified five out of seven stents with binary in-stent restenosis (ISR) and 37 of 38 stents without binary ISR. The sensitivity and specificity of 16-slice CT in the evaluation of coronary stents for binary ISR were 71% (95% confidence interval (CI) (29%, 96%)) and 97% (95%CI (86%, 100%)), respectively, exclusive of non-assessable stents. The positive and negative predictive values of 16-slice CT were 83% (95%CI (36%, 100%)) and 95% (95%CI (83%, 99%)), respectively. Conclusion: Sixteen-slice CT has a low sensitivity, but very a high specificity when compared with FCA in the evaluation of coronary stents for ISR.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 360-364 |
| Number of pages | 5 |
| Journal | Internal Medicine Journal |
| Volume | 37 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 2007 |
| Externally published | Yes |
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Keywords
- In-stent restenosis
- Percutaneous coronary intervention
ASJC Scopus subject areas
- Internal Medicine
Cite this
Non-invasive computed tomography angiography in the assessment of coronary stent patency : An Australian experience. / Soon, K. H.; Cox, N.; Chaitowitz, I.; Selvanayagam, J. B.; Farouque, O.; MacGregor, L.; Bell, K. W.; Lim, Y. L.
In: Internal Medicine Journal, Vol. 37, No. 6, 06.2007, p. 360-364.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Non-invasive computed tomography angiography in the assessment of coronary stent patency
T2 - An Australian experience
AU - Soon, K. H.
AU - Cox, N.
AU - Chaitowitz, I.
AU - Selvanayagam, J. B.
AU - Farouque, O.
AU - MacGregor, L.
AU - Bell, K. W.
AU - Lim, Y. L.
PY - 2007/6
Y1 - 2007/6
N2 - Background: This study aimed to evaluate the feasibility and accuracy of 16-slice computed tomography (CT) in the assessment of coronary stent patency. CT coronary angiography (CA) has a high degree of accuracy in the assessment of coronary artery disease compared with invasive selective CA. However, its accuracy in the evaluation of stent patency is not well investigated. Methods: We conducted a retrospective observational study of paired CT coronary angiography (CT-CA) and invasive fluoroscopic coronary angiography (FCA) in 37 patients with 47 coronary stents. CT-CA was carried out with an electrocardiogram-gated 16-slice CT (LightSpeed-16, General Electric (GE), WI, USA). Two CT reporters, blinded to the FCA findings, assessed CT images for stent patency. A cardiologist blinded to CT findings reported FCA. FCA was regarded as the reference standard. Results: A CT-CA could assess 45 of 47 coronary stents (96%). Non-assessable stents on CT-CA were due to motion artefacts and stent-blooming effects. Of those 45 assessable stents, CT-CA correctly identified five out of seven stents with binary in-stent restenosis (ISR) and 37 of 38 stents without binary ISR. The sensitivity and specificity of 16-slice CT in the evaluation of coronary stents for binary ISR were 71% (95% confidence interval (CI) (29%, 96%)) and 97% (95%CI (86%, 100%)), respectively, exclusive of non-assessable stents. The positive and negative predictive values of 16-slice CT were 83% (95%CI (36%, 100%)) and 95% (95%CI (83%, 99%)), respectively. Conclusion: Sixteen-slice CT has a low sensitivity, but very a high specificity when compared with FCA in the evaluation of coronary stents for ISR.
AB - Background: This study aimed to evaluate the feasibility and accuracy of 16-slice computed tomography (CT) in the assessment of coronary stent patency. CT coronary angiography (CA) has a high degree of accuracy in the assessment of coronary artery disease compared with invasive selective CA. However, its accuracy in the evaluation of stent patency is not well investigated. Methods: We conducted a retrospective observational study of paired CT coronary angiography (CT-CA) and invasive fluoroscopic coronary angiography (FCA) in 37 patients with 47 coronary stents. CT-CA was carried out with an electrocardiogram-gated 16-slice CT (LightSpeed-16, General Electric (GE), WI, USA). Two CT reporters, blinded to the FCA findings, assessed CT images for stent patency. A cardiologist blinded to CT findings reported FCA. FCA was regarded as the reference standard. Results: A CT-CA could assess 45 of 47 coronary stents (96%). Non-assessable stents on CT-CA were due to motion artefacts and stent-blooming effects. Of those 45 assessable stents, CT-CA correctly identified five out of seven stents with binary in-stent restenosis (ISR) and 37 of 38 stents without binary ISR. The sensitivity and specificity of 16-slice CT in the evaluation of coronary stents for binary ISR were 71% (95% confidence interval (CI) (29%, 96%)) and 97% (95%CI (86%, 100%)), respectively, exclusive of non-assessable stents. The positive and negative predictive values of 16-slice CT were 83% (95%CI (36%, 100%)) and 95% (95%CI (83%, 99%)), respectively. Conclusion: Sixteen-slice CT has a low sensitivity, but very a high specificity when compared with FCA in the evaluation of coronary stents for ISR.
KW - In-stent restenosis
KW - Percutaneous coronary intervention
UR - http://www.scopus.com/inward/record.url?scp=34447101741&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34447101741&partnerID=8YFLogxK
U2 - 10.1111/j.1445-5994.2007.01363.x
DO - 10.1111/j.1445-5994.2007.01363.x
M3 - Article
C2 - 17535378
AN - SCOPUS:34447101741
VL - 37
SP - 360
EP - 364
JO - Internal Medicine Journal
JF - Internal Medicine Journal
SN - 1444-0903
IS - 6
ER -