Non-glutamatergic neurotransmission: Role in ischemic brain injury

M. Y.T. Globus, M. D. Ginsberg

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations

Abstract

It is firmly established that excitotoxic mechanisms play an important role in ischemic neuronal damage. The evidence reviewed suggest that glutamate is not the only neurotransmitter involved but rather multiple neurotransmitter/neuromodulatory system participate in mediating neuronal damage. While some of these neurotransmitter act in concert, others may have opposing effects. This raises the possibility that multiple-drug therapy aimed at different sites may prove to be beneficial in the treatment of stroke.

Original languageEnglish (US)
Title of host publicationNeurotransmission and cerebrovascular function vol. 2
Subtitle of host publicationproceedings of the International Symposium 'Neurotransmission and Cerebrovascular Function'. ICS870
EditorsJ. Seylas, R. Sercombe, J. Seylas, R. Sercombe
PublisherElsevier Science Publishers B.V.
Pages467-480
Number of pages14
ISBN (Print)0444811427
StatePublished - Dec 1 1989
EventThe International Symposium 'Neurotransmission and Cerebrovascular Function' -
Duration: Jun 2 1989Jun 5 1989

Publication series

NameNeurotransmission and cerebrovascular function vol. 2: proceedings of the International Symposium 'Neurotransmission and Cerebrovascular Function'. ICS870

Other

OtherThe International Symposium 'Neurotransmission and Cerebrovascular Function'
Period6/2/896/5/89

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Non-glutamatergic neurotransmission: Role in ischemic brain injury'. Together they form a unique fingerprint.

Cite this