Non-glutamatergic neurotransmission: Role in ischemic brain injury

M. Y T Globus, Myron Ginsberg

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Citations (Scopus)

Abstract

It is firmly established that excitotoxic mechanisms play an important role in ischemic neuronal damage. The evidence reviewed suggest that glutamate is not the only neurotransmitter involved but rather multiple neurotransmitter/neuromodulatory system participate in mediating neuronal damage. While some of these neurotransmitter act in concert, others may have opposing effects. This raises the possibility that multiple-drug therapy aimed at different sites may prove to be beneficial in the treatment of stroke.

Original languageEnglish
Title of host publicationNeurotransmission and cerebrovascular function vol. 2: proceedings of the International Symposium 'Neurotransmission and Cerebrovascular Function'. ICS870
EditorsJ. Seylas, R. Sercombe, J. Seylas, R. Sercombe
PublisherElsevier Science Publishers B.V.
Pages467-480
Number of pages14
ISBN (Print)0444811427
StatePublished - Dec 1 1989
EventThe International Symposium 'Neurotransmission and Cerebrovascular Function' -
Duration: Jun 2 1989Jun 5 1989

Other

OtherThe International Symposium 'Neurotransmission and Cerebrovascular Function'
Period6/2/896/5/89

Fingerprint

Synaptic Transmission
Brain Injuries
Neurotransmitter Agents
Glutamic Acid
Stroke
Drug Therapy
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Globus, M. Y. T., & Ginsberg, M. (1989). Non-glutamatergic neurotransmission: Role in ischemic brain injury. In J. Seylas, R. Sercombe, J. Seylas, & R. Sercombe (Eds.), Neurotransmission and cerebrovascular function vol. 2: proceedings of the International Symposium 'Neurotransmission and Cerebrovascular Function'. ICS870 (pp. 467-480). Elsevier Science Publishers B.V..

Non-glutamatergic neurotransmission : Role in ischemic brain injury. / Globus, M. Y T; Ginsberg, Myron.

Neurotransmission and cerebrovascular function vol. 2: proceedings of the International Symposium 'Neurotransmission and Cerebrovascular Function'. ICS870. ed. / J. Seylas; R. Sercombe; J. Seylas; R. Sercombe. Elsevier Science Publishers B.V., 1989. p. 467-480.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Globus, MYT & Ginsberg, M 1989, Non-glutamatergic neurotransmission: Role in ischemic brain injury. in J Seylas, R Sercombe, J Seylas & R Sercombe (eds), Neurotransmission and cerebrovascular function vol. 2: proceedings of the International Symposium 'Neurotransmission and Cerebrovascular Function'. ICS870. Elsevier Science Publishers B.V., pp. 467-480, The International Symposium 'Neurotransmission and Cerebrovascular Function', 6/2/89.
Globus MYT, Ginsberg M. Non-glutamatergic neurotransmission: Role in ischemic brain injury. In Seylas J, Sercombe R, Seylas J, Sercombe R, editors, Neurotransmission and cerebrovascular function vol. 2: proceedings of the International Symposium 'Neurotransmission and Cerebrovascular Function'. ICS870. Elsevier Science Publishers B.V. 1989. p. 467-480
Globus, M. Y T ; Ginsberg, Myron. / Non-glutamatergic neurotransmission : Role in ischemic brain injury. Neurotransmission and cerebrovascular function vol. 2: proceedings of the International Symposium 'Neurotransmission and Cerebrovascular Function'. ICS870. editor / J. Seylas ; R. Sercombe ; J. Seylas ; R. Sercombe. Elsevier Science Publishers B.V., 1989. pp. 467-480
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