Nomenclature report on the major histocompatibility complex genes and alleles of Great Ape, Old and New World monkey species

Natasja G. De Groot, Nel Otting, James Robinson, Antoine Blancher, Bernard A.P. Lafont, Steven G.E. Marsh, David H. O'Connor, Takashi Shiina, Lutz Walter, David I. Watkins, Ronald E. Bontrop

Research output: Contribution to journalArticle

69 Scopus citations

Abstract

The major histocompatibility complex (MHC) plays a central role in the adaptive immune response. The MHC region is characterised by a high gene density, and most of these genes display considerable polymorphism. Next to humans, non-human primates (NHP) are well studied for their MHC. The present nomenclature report provides the scientific community with the latest nomenclature guidelines/rules and current implemented nomenclature revisions for Great Ape, Old and New World monkey species. All the currently published MHC data for the different Great Ape, Old and New World monkey species are archived at the Immuno Polymorphism Database (IPD)-MHC NHP database. The curators of the IPD-MHC NHP database are, in addition, responsible for providing official designations for newly detected polymorphisms.

Original languageEnglish (US)
Pages (from-to)615-631
Number of pages17
JournalImmunogenetics
Volume64
Issue number8
DOIs
StatePublished - Aug 1 2012

Keywords

  • Database
  • IPD
  • MHC
  • NHP
  • Nomenclature

ASJC Scopus subject areas

  • Immunology
  • Genetics

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    De Groot, N. G., Otting, N., Robinson, J., Blancher, A., Lafont, B. A. P., Marsh, S. G. E., O'Connor, D. H., Shiina, T., Walter, L., Watkins, D. I., & Bontrop, R. E. (2012). Nomenclature report on the major histocompatibility complex genes and alleles of Great Ape, Old and New World monkey species. Immunogenetics, 64(8), 615-631. https://doi.org/10.1007/s00251-012-0617-1