NOE enhancements and T1 relaxation times of phosphorylated metabolites in human calf muscle at 1.5 Tesla

T. R. Brown, Radka Stoyanova, T. Greenberg, R. Srinivasan, J. Murphy-Boesch

Research output: Contribution to journalArticle

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Abstract

Nuclear Overhauser effect (NOE) enhancements and relaxation times of 31P metabolites in human calf were measured in 12 volunteers (4 men and 8 women) at 1.5 T using a dual tuned four-ring birdcage. The NOE enhancements of inorganic phosphate (P(i)), phosphocreatine (PCr), γ-, α-, and β- nucleoside triphosphate (NTP) from 19 measurements were 0.51 ± 0.10, 0.64 ± 0.03, 0.53 ± 0.03, 0.56 ± 0.08, and 0.47 ± 0.05, respectively. The relaxation times were independent of proton irradiation and from 23 measurements were 3.49 ± 0.35, 4.97 ± 0.58, 4.07 ± 0.36, 2.90 ± 0.25, and 3.61 ± 0.25 s for P(i), PCr, γ-, α-, and β-NTP, respectively. No significant differences between gender and age were observed for either NOE enhancements or relaxation times. Also, among nine volunteers, we observed no significant differences in T1 between the coupled and decoupled cases.

Original languageEnglish
Pages (from-to)417-421
Number of pages5
JournalMagnetic Resonance in Medicine
Volume33
Issue number3
DOIs
StatePublished - Mar 14 1995
Externally publishedYes

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Phosphocreatine
Nucleosides
Muscles
Volunteers
Protons
Phosphates
triphosphoric acid

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

NOE enhancements and T1 relaxation times of phosphorylated metabolites in human calf muscle at 1.5 Tesla. / Brown, T. R.; Stoyanova, Radka; Greenberg, T.; Srinivasan, R.; Murphy-Boesch, J.

In: Magnetic Resonance in Medicine, Vol. 33, No. 3, 14.03.1995, p. 417-421.

Research output: Contribution to journalArticle

Brown, T. R. ; Stoyanova, Radka ; Greenberg, T. ; Srinivasan, R. ; Murphy-Boesch, J. / NOE enhancements and T1 relaxation times of phosphorylated metabolites in human calf muscle at 1.5 Tesla. In: Magnetic Resonance in Medicine. 1995 ; Vol. 33, No. 3. pp. 417-421.
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