TY - JOUR
T1 - NOE Enhancements and T1 Relaxation Times of Phosphorylated Metabolites in Human Calf Muscle at 1.5 Tesla
AU - Brown, Truman R.
AU - Stoyanova, Radka
AU - Greenberg, Tamela
AU - Srinivasan, Ravi
AU - Murphy‐Boesch, Joseph
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1995/3
Y1 - 1995/3
N2 - Nuclear Overhauser effect (NOE) enhancements and relaxation times of 31P metabolites in human calf were measured in 12 volunteers (4 men and 8 women) at 1.5 T using a dual tuned four-ring birdcage. The NOE enhancements of inorganic phosphate (P(i)), phosphocreatine (PCr), γ-, α-, and β- nucleoside triphosphate (NTP) from 19 measurements were 0.51 ± 0.10, 0.64 ± 0.03, 0.53 ± 0.03, 0.56 ± 0.08, and 0.47 ± 0.05, respectively. The relaxation times were independent of proton irradiation and from 23 measurements were 3.49 ± 0.35, 4.97 ± 0.58, 4.07 ± 0.36, 2.90 ± 0.25, and 3.61 ± 0.25 s for P(i), PCr, γ-, α-, and β-NTP, respectively. No significant differences between gender and age were observed for either NOE enhancements or relaxation times. Also, among nine volunteers, we observed no significant differences in T1 between the coupled and decoupled cases.
AB - Nuclear Overhauser effect (NOE) enhancements and relaxation times of 31P metabolites in human calf were measured in 12 volunteers (4 men and 8 women) at 1.5 T using a dual tuned four-ring birdcage. The NOE enhancements of inorganic phosphate (P(i)), phosphocreatine (PCr), γ-, α-, and β- nucleoside triphosphate (NTP) from 19 measurements were 0.51 ± 0.10, 0.64 ± 0.03, 0.53 ± 0.03, 0.56 ± 0.08, and 0.47 ± 0.05, respectively. The relaxation times were independent of proton irradiation and from 23 measurements were 3.49 ± 0.35, 4.97 ± 0.58, 4.07 ± 0.36, 2.90 ± 0.25, and 3.61 ± 0.25 s for P(i), PCr, γ-, α-, and β-NTP, respectively. No significant differences between gender and age were observed for either NOE enhancements or relaxation times. Also, among nine volunteers, we observed no significant differences in T1 between the coupled and decoupled cases.
KW - decoupled P
KW - in vivo human muscle
KW - nuclear Overhauser effect (NOE)
KW - relaxation times
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U2 - 10.1002/mrm.1910330316
DO - 10.1002/mrm.1910330316
M3 - Article
C2 - 7760710
AN - SCOPUS:0028986038
VL - 33
SP - 417
EP - 421
JO - Magnetic Resonance in Medicine
JF - Magnetic Resonance in Medicine
SN - 0740-3194
IS - 3
ER -