No significant muscle atrophy occurs in first dorsal interosseus muscle after incomplete cervical spinal cord injury

A. Teunissen, R. Bakels, Christine K Thomas, D. Mulder, I. Zijdewind

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Purpose: Following spinal cord injury (SCI), atrophy is often observed in muscles innervated from spinal segments below the lesion. We used the twitch interpolation technique to estimate the total force capacity of the first dorsal interosseus muscle (FDI, index finger abductor) and compared these data to the maximal voluntary contraction (MVC) actually produced by the subject. Methods: Four SCI subjects who had partial voluntary control over their hand muscles, 7 control SCI subjects with intact hand function and 10 able-bodied subjects (AB) performed 3 MVCs and 3 voluntary contractions at 10, 30, 50 and 70% MVC with the right FDI muscle. During the contractions the ulnar nerve was electrically activated (two pulses, interval 10 ms). Muscle force evoked by the stimulation was expressed as a percentage of the potentiated rest twitch and plotted against the background force. Results: MVCs were smaller in the incomplete SCI-group (19.1±3.5N, p<0.005) compared to the control SCI group (40.8±9.1N) and AB-controls (38.1±10.2N). However, the total force capacity as estimated on the basis of regression analysis between the superimposed twitch and background forces resulted in similar forces for all groups (incomplete SCI: 28.5±7.3N, control SCI: 36.4±16.0N, AB-controls: 30.3±6.2N). Conclusion: Comparable total force capacity for all groups suggests that muscle atrophy was insignificant in the SCI-subjects with incomplete injuries.

Original languageEnglish
Title of host publicationAssistive Technology Research Series
Pages338-340
Number of pages3
Volume26
DOIs
StatePublished - Dec 1 2010

Publication series

NameAssistive Technology Research Series
Volume26
ISSN (Print)1383813X
ISSN (Electronic)18798071

Fingerprint

Muscular Atrophy
Spinal Cord Injuries
Muscle
Muscles
Hand
Ulnar Nerve
Cervical Cord
Regression analysis
Fingers
Atrophy
Interpolation
Regression Analysis
Wounds and Injuries

Keywords

  • first dorsal interosseus
  • incomplete spinal cord injury
  • muscle atrophy
  • total muscle force
  • twitch interpolation technique

ASJC Scopus subject areas

  • Engineering (miscellaneous)
  • Medicine (miscellaneous)

Cite this

Teunissen, A., Bakels, R., Thomas, C. K., Mulder, D., & Zijdewind, I. (2010). No significant muscle atrophy occurs in first dorsal interosseus muscle after incomplete cervical spinal cord injury. In Assistive Technology Research Series (Vol. 26, pp. 338-340). (Assistive Technology Research Series; Vol. 26). https://doi.org/10.3233/978-1-60750-080-3-338

No significant muscle atrophy occurs in first dorsal interosseus muscle after incomplete cervical spinal cord injury. / Teunissen, A.; Bakels, R.; Thomas, Christine K; Mulder, D.; Zijdewind, I.

Assistive Technology Research Series. Vol. 26 2010. p. 338-340 (Assistive Technology Research Series; Vol. 26).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Teunissen, A, Bakels, R, Thomas, CK, Mulder, D & Zijdewind, I 2010, No significant muscle atrophy occurs in first dorsal interosseus muscle after incomplete cervical spinal cord injury. in Assistive Technology Research Series. vol. 26, Assistive Technology Research Series, vol. 26, pp. 338-340. https://doi.org/10.3233/978-1-60750-080-3-338
Teunissen A, Bakels R, Thomas CK, Mulder D, Zijdewind I. No significant muscle atrophy occurs in first dorsal interosseus muscle after incomplete cervical spinal cord injury. In Assistive Technology Research Series. Vol. 26. 2010. p. 338-340. (Assistive Technology Research Series). https://doi.org/10.3233/978-1-60750-080-3-338
Teunissen, A. ; Bakels, R. ; Thomas, Christine K ; Mulder, D. ; Zijdewind, I. / No significant muscle atrophy occurs in first dorsal interosseus muscle after incomplete cervical spinal cord injury. Assistive Technology Research Series. Vol. 26 2010. pp. 338-340 (Assistive Technology Research Series).
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AB - Purpose: Following spinal cord injury (SCI), atrophy is often observed in muscles innervated from spinal segments below the lesion. We used the twitch interpolation technique to estimate the total force capacity of the first dorsal interosseus muscle (FDI, index finger abductor) and compared these data to the maximal voluntary contraction (MVC) actually produced by the subject. Methods: Four SCI subjects who had partial voluntary control over their hand muscles, 7 control SCI subjects with intact hand function and 10 able-bodied subjects (AB) performed 3 MVCs and 3 voluntary contractions at 10, 30, 50 and 70% MVC with the right FDI muscle. During the contractions the ulnar nerve was electrically activated (two pulses, interval 10 ms). Muscle force evoked by the stimulation was expressed as a percentage of the potentiated rest twitch and plotted against the background force. Results: MVCs were smaller in the incomplete SCI-group (19.1±3.5N, p<0.005) compared to the control SCI group (40.8±9.1N) and AB-controls (38.1±10.2N). However, the total force capacity as estimated on the basis of regression analysis between the superimposed twitch and background forces resulted in similar forces for all groups (incomplete SCI: 28.5±7.3N, control SCI: 36.4±16.0N, AB-controls: 30.3±6.2N). Conclusion: Comparable total force capacity for all groups suggests that muscle atrophy was insignificant in the SCI-subjects with incomplete injuries.

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