The knowledge and the information about Renin Angiotensin System and Arginine-Nitric Oxide pathway helped us in understanding more about cardiac, vascular and renal systems, their function, the physiology, and pathophysiology of different diseases that may affect them. The existence of a Nitric Oxide/Angiotensin II axis, brought modification to our ways of thinking with new and more pathophysiological approaches to the treatment of hypertension and end-organ disease. There appears to be a link between hypertension, salt sensitivity, endothelial function and NO-AngII axis on one side and end organ damage on the other side. Anti-hypertensive agents that can restore endothelial function beside their antihypertensive effect, may be better in preventing or at least slowing end-organ damage.
|Original language||English (US)|
|Number of pages||10|
|Journal||Journal of Nephrology|
|State||Published - May 1 2000|
- Angiotensin II
- Nitric oxide
ASJC Scopus subject areas