Nitrate-selective electrode based on a cyclic bis-thiourea ionophore

Amanda S. Watts, Vasilis G. Gavalas, Arthur Cammers, Pilar Sánchez Andrada, Mateo Alajarín, Leonidas G. Bachas

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

Compounds containing urea and thiourea groups can hydrogen bond oxoanions and, as such, represent a class of potential ionophores for anion-selective electrodes. We have evaluated cyclic and linear bis-thiourea compounds as ionophores in polymer membrane ion-selective electrodes. An improvement in the selectivity coefficient of nitrate against chloride of greater than one order of magnitude was observed with the cyclic ionophore in comparison to the Hofmeister lipophilicity series (log KN O3-, C l-pot of -3.50 with ionophore versus -2.40 with no bis-thiourea ionophore), indicating the preference of the cyclic ionophore for nitrate. This preference for nitrate over chloride may be attributed to the spatial arrangement of the thiourea hydrogen atoms, which are capable of forming hydrogen bonds with nitrate, as well as the size of the ionophore binding cavity. In the lowest-energy conformation, all thiourea hydrogen atoms point toward a putative nitrate binding site, likely contributing to enhanced coordination.

Original languageEnglish (US)
Pages (from-to)200-207
Number of pages8
JournalSensors and Actuators, B: Chemical
Volume121
Issue number1
DOIs
StatePublished - Jan 30 2007

Keywords

  • Bis-thiourea
  • Ion-selective electrode
  • Ionophore
  • Nitrate

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Instrumentation
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Electrical and Electronic Engineering
  • Materials Chemistry

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