TY - JOUR
T1 - Nightly variability in the indices of sleep-disordered breathing in men being evaluated for impotence with consecutive night polysomnograms
AU - Chediak, Alejandro D.
AU - Acevedo-Crespo, Juan C.
AU - Seiden, David J.
AU - Kim, Helen H.
AU - Kiel, Michael H.
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1996
Y1 - 1996
N2 - We retrospectively analyzed night-to-night variability in the indices of sleep apnea in a group of men who underwent consecutive polysomnograms (PSGs) in the evaluation of impotence. The study group consisted of 37 subjects. Fifty-seven percent of the subjects had an apnea/hypopnea index (AHI) of 5 or more on the first PSG, whereas 70% met this criterion on the second study. On both PSGs, 49% of the subjects exhibited an AHI of 10 or more. The AHI varied by 10 or more between the two PSGs in 32% of the cases. Using a threshold AHI of 5 or more to establish a diagnosis of sleep apnea, 22% of the subjects would not have been diagnosed by the first PSG, and the false negative rate for the first PSG was 50%. The variability observed in the AHI could not be explained by differences in total sleep time, sleep stages 11 through 4 and rapid eye movement (REM) sleep]; the amount of time sleeping supine, or a combination of sleep stage and position. The mean AHI, the apnea/hypopnea- related nadir, and the mean oxyhemoglobin saturation did not differ among the two PSGs. Our observations support the notion that for groups of subjects the mean AHI is relatively constant across 2 nights of study in the sleep laboratory. However, when an AHI of 5 or l0 or more is the sole criterion used to establish the diagnosis of sleep apnea, a single PSG may not be sufficient to rule out the presence of a sleep apnea syndrome.
AB - We retrospectively analyzed night-to-night variability in the indices of sleep apnea in a group of men who underwent consecutive polysomnograms (PSGs) in the evaluation of impotence. The study group consisted of 37 subjects. Fifty-seven percent of the subjects had an apnea/hypopnea index (AHI) of 5 or more on the first PSG, whereas 70% met this criterion on the second study. On both PSGs, 49% of the subjects exhibited an AHI of 10 or more. The AHI varied by 10 or more between the two PSGs in 32% of the cases. Using a threshold AHI of 5 or more to establish a diagnosis of sleep apnea, 22% of the subjects would not have been diagnosed by the first PSG, and the false negative rate for the first PSG was 50%. The variability observed in the AHI could not be explained by differences in total sleep time, sleep stages 11 through 4 and rapid eye movement (REM) sleep]; the amount of time sleeping supine, or a combination of sleep stage and position. The mean AHI, the apnea/hypopnea- related nadir, and the mean oxyhemoglobin saturation did not differ among the two PSGs. Our observations support the notion that for groups of subjects the mean AHI is relatively constant across 2 nights of study in the sleep laboratory. However, when an AHI of 5 or l0 or more is the sole criterion used to establish the diagnosis of sleep apnea, a single PSG may not be sufficient to rule out the presence of a sleep apnea syndrome.
KW - Impotence
KW - Sexual dysfunction
KW - Sleep apnea
KW - Sleep-disordered breathing
KW - Variability
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U2 - 10.1093/sleep/19.7.589
DO - 10.1093/sleep/19.7.589
M3 - Article
C2 - 8899939
AN - SCOPUS:0029793963
VL - 19
SP - 589
EP - 592
JO - Sleep
JF - Sleep
SN - 0161-8105
IS - 7
ER -