Nicotine addiction causes unique detrimental effects on women's brains

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Nicotine addiction produces diverse physiological effects common to both men and women because of activation of the nicotinic acetylcholine receptors. In addition to these effects, nicotine reduces circulating estrogen (the female sex hormone) levels and leads to early onset of menopause in women. Nicotine's effect on estrogen metabolism has potential far-reaching consequences because endogenous circulating estrogen helps prevent cerebrovascular diseases in premenopausal women. In this article, the author presents a survey of literature showing that nicotine addiction causes unique deleterious effects in women's brains by inhibiting estrogen signaling, which makes the brain more susceptible to ischemic brain damage.

Original languageEnglish
Pages (from-to)149-158
Number of pages10
JournalJournal of Addictive Diseases
Volume30
Issue number2
DOIs
StatePublished - Apr 1 2011

Fingerprint

Nicotine
Estrogens
Brain
Cerebrovascular Disorders
Nicotinic Receptors
Gonadal Steroid Hormones
Menopause

Keywords

  • Aromatase
  • birth control pills
  • cerebral ischemia
  • estrogen
  • estrogen receptors
  • stroke

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Psychiatry and Mental health
  • Clinical Psychology

Cite this

Nicotine addiction causes unique detrimental effects on women's brains. / Raval, Ami.

In: Journal of Addictive Diseases, Vol. 30, No. 2, 01.04.2011, p. 149-158.

Research output: Contribution to journalArticle

@article{9d56206ca68d4203bc0e09e902c4b305,
title = "Nicotine addiction causes unique detrimental effects on women's brains",
abstract = "Nicotine addiction produces diverse physiological effects common to both men and women because of activation of the nicotinic acetylcholine receptors. In addition to these effects, nicotine reduces circulating estrogen (the female sex hormone) levels and leads to early onset of menopause in women. Nicotine's effect on estrogen metabolism has potential far-reaching consequences because endogenous circulating estrogen helps prevent cerebrovascular diseases in premenopausal women. In this article, the author presents a survey of literature showing that nicotine addiction causes unique deleterious effects in women's brains by inhibiting estrogen signaling, which makes the brain more susceptible to ischemic brain damage.",
keywords = "Aromatase, birth control pills, cerebral ischemia, estrogen, estrogen receptors, stroke",
author = "Ami Raval",
year = "2011",
month = "4",
day = "1",
doi = "10.1080/10550887.2011.554782",
language = "English",
volume = "30",
pages = "149--158",
journal = "Journal of Addictive Diseases",
issn = "1055-0887",
publisher = "Routledge",
number = "2",

}

TY - JOUR

T1 - Nicotine addiction causes unique detrimental effects on women's brains

AU - Raval, Ami

PY - 2011/4/1

Y1 - 2011/4/1

N2 - Nicotine addiction produces diverse physiological effects common to both men and women because of activation of the nicotinic acetylcholine receptors. In addition to these effects, nicotine reduces circulating estrogen (the female sex hormone) levels and leads to early onset of menopause in women. Nicotine's effect on estrogen metabolism has potential far-reaching consequences because endogenous circulating estrogen helps prevent cerebrovascular diseases in premenopausal women. In this article, the author presents a survey of literature showing that nicotine addiction causes unique deleterious effects in women's brains by inhibiting estrogen signaling, which makes the brain more susceptible to ischemic brain damage.

AB - Nicotine addiction produces diverse physiological effects common to both men and women because of activation of the nicotinic acetylcholine receptors. In addition to these effects, nicotine reduces circulating estrogen (the female sex hormone) levels and leads to early onset of menopause in women. Nicotine's effect on estrogen metabolism has potential far-reaching consequences because endogenous circulating estrogen helps prevent cerebrovascular diseases in premenopausal women. In this article, the author presents a survey of literature showing that nicotine addiction causes unique deleterious effects in women's brains by inhibiting estrogen signaling, which makes the brain more susceptible to ischemic brain damage.

KW - Aromatase

KW - birth control pills

KW - cerebral ischemia

KW - estrogen

KW - estrogen receptors

KW - stroke

UR - http://www.scopus.com/inward/record.url?scp=79957470750&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79957470750&partnerID=8YFLogxK

U2 - 10.1080/10550887.2011.554782

DO - 10.1080/10550887.2011.554782

M3 - Article

VL - 30

SP - 149

EP - 158

JO - Journal of Addictive Diseases

JF - Journal of Addictive Diseases

SN - 1055-0887

IS - 2

ER -