Niche Applications of Irreversible Electroporation

Shivank S. Bhatia, Rahul Arya, Govindarajan Narayanan

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Irreversible electroporation (IRE) induces cell death by exposing it to high-voltage, low-energy DC current pulses. The mechanism of cell death and healing is a departure from the other existing technologies such as radiofrequency ablation, microwave ablation, and cryoablation. These thermal ablative technologies have several applications in oncology but have limitations that have also been established. IRE has shown promise to overcome some of these limitations and has enabled the use of an ablative technology in treating lesions close to the bile ducts and vasculature and in organs such as the pancreas. This review highlights some of the niche applications of IRE and the data so far.

Original languageEnglish (US)
Pages (from-to)170-175
Number of pages6
JournalTechniques in Vascular and Interventional Radiology
Issue number3
StatePublished - Sep 1 2015


  • Ablation
  • Irreversible electroporation
  • Niche application
  • Pancreas
  • Vascular

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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