Nexus formation in the myometrium during parturition and induced by estrogen

Gerhard Dahl, W. Berger

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

The occurence of nexuses (gap junctions) in mouse uterine smooth muscle was found to depend on the hormonal state. As revealed by freeze-fracture electron microscopy, nexuses are virtually absent in virginal and pregnant mice. Abundant, large-sized nexuses were observed in the myometrium during parturition. Estrogen application to virginal mice also induced an increase in number and size of nexuses. Our observations indicate that a new formation of nexuses occurs in differentiated cells. New nexuses may be formed by the confluence of nexus subunits preexisting in the cell membrane or by newly biosynthesized components.

Original languageEnglish
Pages (from-to)381-387
Number of pages7
JournalCell Biology International Reports
Volume2
Issue number4
DOIs
StatePublished - Jan 1 1978
Externally publishedYes

Fingerprint

Myometrium
Estrogens
Parturition
Gap Junctions
Smooth Muscle
Electron Microscopy
Cell Membrane
Nexus

ASJC Scopus subject areas

  • Cell Biology

Cite this

Nexus formation in the myometrium during parturition and induced by estrogen. / Dahl, Gerhard; Berger, W.

In: Cell Biology International Reports, Vol. 2, No. 4, 01.01.1978, p. 381-387.

Research output: Contribution to journalArticle

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