Abstract
The occurence of nexuses (gap junctions) in mouse uterine smooth muscle was found to depend on the hormonal state. As revealed by freeze-fracture electron microscopy, nexuses are virtually absent in virginal and pregnant mice. Abundant, large-sized nexuses were observed in the myometrium during parturition. Estrogen application to virginal mice also induced an increase in number and size of nexuses. Our observations indicate that a new formation of nexuses occurs in differentiated cells. New nexuses may be formed by the confluence of nexus subunits preexisting in the cell membrane or by newly biosynthesized components.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 381-387 |
| Number of pages | 7 |
| Journal | Cell Biology International Reports |
| Volume | 2 |
| Issue number | 4 |
| DOIs | |
| State | Published - Jul 1978 |
| Externally published | Yes |
ASJC Scopus subject areas
- Cell Biology
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Dahl, G., & Berger, W. (1978). Nexus formation in the myometrium during parturition and induced by estrogen. Cell Biology International Reports, 2(4), 381-387. https://doi.org/10.1016/0309-1651(78)90024-3