Abstract
The occurence of nexuses (gap junctions) in mouse uterine smooth muscle was found to depend on the hormonal state. As revealed by freeze-fracture electron microscopy, nexuses are virtually absent in virginal and pregnant mice. Abundant, large-sized nexuses were observed in the myometrium during parturition. Estrogen application to virginal mice also induced an increase in number and size of nexuses. Our observations indicate that a new formation of nexuses occurs in differentiated cells. New nexuses may be formed by the confluence of nexus subunits preexisting in the cell membrane or by newly biosynthesized components.
| Original language | English |
|---|---|
| Pages (from-to) | 381-387 |
| Number of pages | 7 |
| Journal | Cell Biology International Reports |
| Volume | 2 |
| Issue number | 4 |
| DOIs | |
| State | Published - Jan 1 1978 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cell Biology
Cite this
Nexus formation in the myometrium during parturition and induced by estrogen. / Dahl, Gerhard; Berger, W.
In: Cell Biology International Reports, Vol. 2, No. 4, 01.01.1978, p. 381-387.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Nexus formation in the myometrium during parturition and induced by estrogen
AU - Dahl, Gerhard
AU - Berger, W.
PY - 1978/1/1
Y1 - 1978/1/1
N2 - The occurence of nexuses (gap junctions) in mouse uterine smooth muscle was found to depend on the hormonal state. As revealed by freeze-fracture electron microscopy, nexuses are virtually absent in virginal and pregnant mice. Abundant, large-sized nexuses were observed in the myometrium during parturition. Estrogen application to virginal mice also induced an increase in number and size of nexuses. Our observations indicate that a new formation of nexuses occurs in differentiated cells. New nexuses may be formed by the confluence of nexus subunits preexisting in the cell membrane or by newly biosynthesized components.
AB - The occurence of nexuses (gap junctions) in mouse uterine smooth muscle was found to depend on the hormonal state. As revealed by freeze-fracture electron microscopy, nexuses are virtually absent in virginal and pregnant mice. Abundant, large-sized nexuses were observed in the myometrium during parturition. Estrogen application to virginal mice also induced an increase in number and size of nexuses. Our observations indicate that a new formation of nexuses occurs in differentiated cells. New nexuses may be formed by the confluence of nexus subunits preexisting in the cell membrane or by newly biosynthesized components.
UR - http://www.scopus.com/inward/record.url?scp=0018202862&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0018202862&partnerID=8YFLogxK
U2 - 10.1016/0309-1651(78)90024-3
DO - 10.1016/0309-1651(78)90024-3
M3 - Article
C2 - 743745
AN - SCOPUS:0018202862
VL - 2
SP - 381
EP - 387
JO - Cell Biology International
JF - Cell Biology International
SN - 1065-6995
IS - 4
ER -