New Therapeutic Options in the Medical Management of Advanced Melanoma

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations

Abstract

During the past 3 decades, the incidence, morbidity, and mortality of malignant melanoma have increased dramatically. Advanced melanoma has remained a disease that is for the most part incurable and has challenged all therapeutic efforts to make a dent in its natural history. Recent advances in the understanding of the molecular alterations in melanoma and in the immunologic mechanisms playing a role in this malignancy have brought hope that significant progress can be achieved, as evidenced by early encouraging clinical data. This review will summarize these recent developments and their impact on current clinical practice.

Original languageEnglish (US)
Pages (from-to)249-257
Number of pages9
JournalSeminars in cutaneous medicine and surgery
Volume29
Issue number4
DOIs
StatePublished - Dec 2010
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Dermatology

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