Abstract
A new one pot synthetic method has been developed for preparing amphiphilic block copolymers. The method makes use of episulfide anionic polymerization for generating symmetric or asymmetric tri- or multiblock copolymers with living mechanism. Important features of the method are (a) the use of in situ generated thiolates, which ensures reproducibility in the initiator concentration; (b) the mild character of the reactive species; therefore, also sensitive bioactive groups could be easily incorporated into the polymer structure; (c) the tolerance to impurities in the reagents and the one pot character, which allow the use of the method also by operators with limited skills in organic synthesis.
| Original language | English |
|---|---|
| Pages (from-to) | 8913-8917 |
| Number of pages | 5 |
| Journal | Macromolecules |
| Volume | 34 |
| Issue number | 26 |
| DOIs | |
| State | Published - Dec 18 2001 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Materials Chemistry
Cite this
New synthetic methodologies for amphiphilic multiblock copolymers of ethylene glycol and propylene sulfide. / Napoli, A.; Tirelli, N.; Kilcher, G.; Hubbell, J. A.
In: Macromolecules, Vol. 34, No. 26, 18.12.2001, p. 8913-8917.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - New synthetic methodologies for amphiphilic multiblock copolymers of ethylene glycol and propylene sulfide
AU - Napoli, A.
AU - Tirelli, N.
AU - Kilcher, G.
AU - Hubbell, J. A.
PY - 2001/12/18
Y1 - 2001/12/18
N2 - A new one pot synthetic method has been developed for preparing amphiphilic block copolymers. The method makes use of episulfide anionic polymerization for generating symmetric or asymmetric tri- or multiblock copolymers with living mechanism. Important features of the method are (a) the use of in situ generated thiolates, which ensures reproducibility in the initiator concentration; (b) the mild character of the reactive species; therefore, also sensitive bioactive groups could be easily incorporated into the polymer structure; (c) the tolerance to impurities in the reagents and the one pot character, which allow the use of the method also by operators with limited skills in organic synthesis.
AB - A new one pot synthetic method has been developed for preparing amphiphilic block copolymers. The method makes use of episulfide anionic polymerization for generating symmetric or asymmetric tri- or multiblock copolymers with living mechanism. Important features of the method are (a) the use of in situ generated thiolates, which ensures reproducibility in the initiator concentration; (b) the mild character of the reactive species; therefore, also sensitive bioactive groups could be easily incorporated into the polymer structure; (c) the tolerance to impurities in the reagents and the one pot character, which allow the use of the method also by operators with limited skills in organic synthesis.
UR - http://www.scopus.com/inward/record.url?scp=0035910205&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035910205&partnerID=8YFLogxK
U2 - 10.1021/ma0108057
DO - 10.1021/ma0108057
M3 - Article
AN - SCOPUS:0035910205
VL - 34
SP - 8913
EP - 8917
JO - Macromolecules
JF - Macromolecules
SN - 0024-9297
IS - 26
ER -