Seizure clusters are common occurrences among patients living with epilepsy. Seizure clustering has a significant impact on patients' emotional wellbeing, work, and quality of life and is associated with increased use of emergency departments. However, rescue treatment options have been limited, impractical, and often rejected by patients. With the advent of nasal spray formulations of seizure rescue treatment, clinicians can offer an option that is easily used. With 75% of patients in the Seizure Cluster Burden of Illness US Study somewhat or strongly agreeing that they live in fear of having a seizure at any time and 70% of adult patients reporting that they do not have a seizure response plan, it is critical that patients adopt Seizure Action Plans and Acute Seizure Action Plans. This report addresses the use of rescue medications and emergency plans to provide treatment for seizure clusters that patients and their caregivers will use.
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