New insights into the link between cardiovascular disease and depression

S. A. Mosovich, R. T. Boone, A. Reichenberg, S. Bansilal, J. Shaffer, K. Dahlman, Philip D Harvey, M. E. Farkouh

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Introduction: Although the association between depression and cardiovascular disease (CVD) is well documented, the underlying mechanisms for this relationship remain unclear. In this paper, we present three possible models which account for the comorbidity between depression and cardiovascular disease. Models: The first model outlines depression as a risk factor for CVD and the second model presents CVD as a risk factor for depression. The third model proposes a common underlying pathway related to the effects of chronic stress on the body in manifesting as depression or cardiovascular disease. Conclusions: If the proposed model holds true, it may be possible that an intervention initiated before overt manifestations of CVD or depression become apparent, may delay or prevent the onset of these serious clinical entities.

Original languageEnglish
Pages (from-to)423-432
Number of pages10
JournalInternational Journal of Clinical Practice
Volume62
Issue number3
DOIs
StatePublished - Mar 1 2008
Externally publishedYes

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Cardiovascular Diseases
Comorbidity

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Mosovich, S. A., Boone, R. T., Reichenberg, A., Bansilal, S., Shaffer, J., Dahlman, K., ... Farkouh, M. E. (2008). New insights into the link between cardiovascular disease and depression. International Journal of Clinical Practice, 62(3), 423-432. https://doi.org/10.1111/j.1742-1241.2007.01640.x

New insights into the link between cardiovascular disease and depression. / Mosovich, S. A.; Boone, R. T.; Reichenberg, A.; Bansilal, S.; Shaffer, J.; Dahlman, K.; Harvey, Philip D; Farkouh, M. E.

In: International Journal of Clinical Practice, Vol. 62, No. 3, 01.03.2008, p. 423-432.

Research output: Contribution to journalArticle

Mosovich, SA, Boone, RT, Reichenberg, A, Bansilal, S, Shaffer, J, Dahlman, K, Harvey, PD & Farkouh, ME 2008, 'New insights into the link between cardiovascular disease and depression', International Journal of Clinical Practice, vol. 62, no. 3, pp. 423-432. https://doi.org/10.1111/j.1742-1241.2007.01640.x
Mosovich SA, Boone RT, Reichenberg A, Bansilal S, Shaffer J, Dahlman K et al. New insights into the link between cardiovascular disease and depression. International Journal of Clinical Practice. 2008 Mar 1;62(3):423-432. https://doi.org/10.1111/j.1742-1241.2007.01640.x
Mosovich, S. A. ; Boone, R. T. ; Reichenberg, A. ; Bansilal, S. ; Shaffer, J. ; Dahlman, K. ; Harvey, Philip D ; Farkouh, M. E. / New insights into the link between cardiovascular disease and depression. In: International Journal of Clinical Practice. 2008 ; Vol. 62, No. 3. pp. 423-432.
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