TY - JOUR
T1 - New frontiers in calvarial reconstruction
T2 - Integrating computer-assisted design and tissue engineering in cranioplasty
AU - Chim, Harvey
AU - Schantz, Jan Thorsten
N1 - Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2005/11
Y1 - 2005/11
N2 - Repair of large and complex calvarial defects remains a particular challenge for reconstruction. The paucity of techniques and materials emphasizes the need for alternative bone formation strategies. Recent integrative approaches suggest that successful reconstruction requires interdisciplinary teams, with surgeons interacting with imaging experts, materials scientists, and engineers. In this review, the authors present an overview of current materials used in calvarial reconstruction. Subsequently, progress in computer-designed prostheses, tissue engineering, and osteoinduction strategies is discussed. Finally, the authors discuss their experience with the integration of computer-aided fabrication of customized implants and tissue engineering for calvarial reconstruction.
AB - Repair of large and complex calvarial defects remains a particular challenge for reconstruction. The paucity of techniques and materials emphasizes the need for alternative bone formation strategies. Recent integrative approaches suggest that successful reconstruction requires interdisciplinary teams, with surgeons interacting with imaging experts, materials scientists, and engineers. In this review, the authors present an overview of current materials used in calvarial reconstruction. Subsequently, progress in computer-designed prostheses, tissue engineering, and osteoinduction strategies is discussed. Finally, the authors discuss their experience with the integration of computer-aided fabrication of customized implants and tissue engineering for calvarial reconstruction.
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U2 - 10.1097/01.prs.0000182386.78775.cd
DO - 10.1097/01.prs.0000182386.78775.cd
M3 - Review article
C2 - 16267439
AN - SCOPUS:27744526166
VL - 116
SP - 1726
EP - 1741
JO - Plastic and Reconstructive Surgery
JF - Plastic and Reconstructive Surgery
SN - 0032-1052
IS - 6
ER -