New collagen markers of 'derepression' synthesized by rabbit articular chondrocytes in culture

Herman S. Cheung, Wilson Harvey, Paul D. Benya, Marcel E. Nimni

Research output: Contribution to journalArticle

43 Scopus citations

Abstract

Chondrocytes isolated from rabbit articular cartilage undergo a progressive 'derepression' in culture and synthesize Type I, Type III and an unidentified collagen designated Peak 'X'. In contrast, cartilage slices synthesize predominantly Type II collagen with increasing amounts of Peak 'X' during prolonged culture.

Original languageEnglish (US)
Pages (from-to)1371-1378
Number of pages8
JournalBiochemical and biophysical research communications
Volume68
Issue number4
DOIs
StatePublished - Feb 23 1976
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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