Neutrophil Chemotactic Activity in Human Gastric Secretions

Robert A. Kozol, Amalia Punzo, Randall Ribaudo, Edward F. Rossomando, Salwa A. Elgebaly

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

To study levels of neutrophil chemotactic activity in human gastric secretions, these secretions were collected via the endoscope during elective esophagogastroduodenoscopy. Fresh samples were then prepared for the neutrophil chemotactic assay with the use of human peripheral neutrophils in modified Boyden chambers. Mean maximum chemotactic activity was 45.8% ± 11.2% in patients with gastric inflammation compared with only 10.1% ± 4.2% in patients with normal results of endoscopic examination. The chemotactic factors responsible for this chemotactic activity may play a role in the recruitment of neutrophils to areas of gastric mucosal injury.

Original languageEnglish (US)
Pages (from-to)454-456
Number of pages3
JournalArchives of Surgery
Volume125
Issue number4
DOIs
StatePublished - Apr 1990

ASJC Scopus subject areas

  • Surgery

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    Kozol, R. A., Punzo, A., Ribaudo, R., Rossomando, E. F., & Elgebaly, S. A. (1990). Neutrophil Chemotactic Activity in Human Gastric Secretions. Archives of Surgery, 125(4), 454-456. https://doi.org/10.1001/archsurg.1990.01410160040008