Neuropathic pain and dry eye

Anat Galor, Hamid Reza Moein, Charity Lee, Adriana Rodriguez, Elizabeth Felix, Konstantinos D. Sarantopoulos, Roy C Levitt

Research output: Contribution to journalReview article

26 Scopus citations


Dry eye is a common, multifactorial disease currently diagnosed by a combination of symptoms and signs. Its epidemiology and clinical presentation have many similarities with neuropathic pain outside the eye. This review highlights the similarities between dry eye and neuropathic pain, focusing on clinical features, somatosensory function, and underlying pathophysiology. Implications of these similarities on the diagnosis and treatment of dry eye are discussed.

Original languageEnglish (US)
Pages (from-to)31-44
Number of pages14
JournalOcular Surface
Issue number1
StatePublished - Jan 1 2018



  • Dry eye
  • Genetics
  • Inflammation
  • Nerve sensitization
  • Neuropathic pain
  • Treatment

ASJC Scopus subject areas

  • Ophthalmology

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