Neuropathic pain and dry eye

Anat Galor; Hamid Reza Moein; Charity Lee; Adriana Rodriguez; Elizabeth R. Felix; Konstantinos D. Sarantopoulos; Roy C. Levitt

doi:10.1016/j.jtos.2017.10.001

Neuropathic pain and dry eye

Anat Galor, Hamid Reza Moein, Charity Lee, Adriana Rodriguez, Elizabeth R. Felix, Konstantinos D. Sarantopoulos, Roy C. Levitt

Research output: Contribution to journal › Review article › peer-review

45 Scopus citations

Abstract

Dry eye is a common, multifactorial disease currently diagnosed by a combination of symptoms and signs. Its epidemiology and clinical presentation have many similarities with neuropathic pain outside the eye. This review highlights the similarities between dry eye and neuropathic pain, focusing on clinical features, somatosensory function, and underlying pathophysiology. Implications of these similarities on the diagnosis and treatment of dry eye are discussed.

Original language	English (US)
Pages (from-to)	31-44
Number of pages	14
Journal	Ocular Surface
Volume	16
Issue number	1
DOIs	https://doi.org/10.1016/j.jtos.2017.10.001
State	Published - Jan 2018

Keywords

Dry eye
Genetics
Inflammation
Nerve sensitization
Neuropathic pain
Treatment

ASJC Scopus subject areas

Ophthalmology

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10.1016/j.jtos.2017.10.001

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