Neuropathic pain and dry eye

Anat Galor, Hamid Reza Moein, Charity Lee, Adriana Rodriguez, Elizabeth Felix, Konstantinos D. Sarantopoulos, Roy C Levitt

Research output: Contribution to journal › Review article

20 Citations (Scopus)

Abstract

Dry eye is a common, multifactorial disease currently diagnosed by a combination of symptoms and signs. Its epidemiology and clinical presentation have many similarities with neuropathic pain outside the eye. This review highlights the similarities between dry eye and neuropathic pain, focusing on clinical features, somatosensory function, and underlying pathophysiology. Implications of these similarities on the diagnosis and treatment of dry eye are discussed.

Original languageEnglish (US)
Pages (from-to)31-44
Number of pages14
JournalOcular Surface
Volume16
Issue number1
DOIs
StatePublished - Jan 1 2018

Fingerprint

Neuralgia
Eye Pain
Signs and Symptoms
Epidemiology
Therapeutics

Keywords

  • Dry eye
  • Genetics
  • Inflammation
  • Nerve sensitization
  • Neuropathic pain
  • Treatment

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Neuropathic pain and dry eye. / Galor, Anat; Moein, Hamid Reza; Lee, Charity; Rodriguez, Adriana; Felix, Elizabeth; Sarantopoulos, Konstantinos D.; Levitt, Roy C.

In: Ocular Surface, Vol. 16, No. 1, 01.01.2018, p. 31-44.

Research output: Contribution to journal › Review article

Galor, A, Moein, HR, Lee, C, Rodriguez, A, Felix, E, Sarantopoulos, KD & Levitt, RC 2018, 'Neuropathic pain and dry eye', Ocular Surface, vol. 16, no. 1, pp. 31-44. https://doi.org/10.1016/j.jtos.2017.10.001
Galor A, Moein HR, Lee C, Rodriguez A, Felix E, Sarantopoulos KD et al. Neuropathic pain and dry eye. Ocular Surface. 2018 Jan 1;16(1):31-44. https://doi.org/10.1016/j.jtos.2017.10.001
Galor, Anat ; Moein, Hamid Reza ; Lee, Charity ; Rodriguez, Adriana ; Felix, Elizabeth ; Sarantopoulos, Konstantinos D. ; Levitt, Roy C. / Neuropathic pain and dry eye. In: Ocular Surface. 2018 ; Vol. 16, No. 1. pp. 31-44.
@article{93c8f3efc9f04d67af51bd30da965cac,
title = "Neuropathic pain and dry eye",
abstract = "Dry eye is a common, multifactorial disease currently diagnosed by a combination of symptoms and signs. Its epidemiology and clinical presentation have many similarities with neuropathic pain outside the eye. This review highlights the similarities between dry eye and neuropathic pain, focusing on clinical features, somatosensory function, and underlying pathophysiology. Implications of these similarities on the diagnosis and treatment of dry eye are discussed.",
keywords = "Dry eye, Genetics, Inflammation, Nerve sensitization, Neuropathic pain, Treatment",
author = "Anat Galor and Moein, {Hamid Reza} and Charity Lee and Adriana Rodriguez and Elizabeth Felix and Sarantopoulos, {Konstantinos D.} and Levitt, {Roy C}",
year = "2018",
month = "1",
day = "1",
doi = "10.1016/j.jtos.2017.10.001",
language = "English (US)",
volume = "16",
pages = "31--44",
journal = "Ocular Surface",
issn = "1542-0124",
publisher = "Ethis Communications, Inc.",
number = "1",

}

TY - JOUR

T1 - Neuropathic pain and dry eye

AU - Galor, Anat

AU - Moein, Hamid Reza

AU - Lee, Charity

AU - Rodriguez, Adriana

AU - Felix, Elizabeth

AU - Sarantopoulos, Konstantinos D.

AU - Levitt, Roy C

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Dry eye is a common, multifactorial disease currently diagnosed by a combination of symptoms and signs. Its epidemiology and clinical presentation have many similarities with neuropathic pain outside the eye. This review highlights the similarities between dry eye and neuropathic pain, focusing on clinical features, somatosensory function, and underlying pathophysiology. Implications of these similarities on the diagnosis and treatment of dry eye are discussed.

AB - Dry eye is a common, multifactorial disease currently diagnosed by a combination of symptoms and signs. Its epidemiology and clinical presentation have many similarities with neuropathic pain outside the eye. This review highlights the similarities between dry eye and neuropathic pain, focusing on clinical features, somatosensory function, and underlying pathophysiology. Implications of these similarities on the diagnosis and treatment of dry eye are discussed.

KW - Dry eye

KW - Genetics

KW - Inflammation

KW - Nerve sensitization

KW - Neuropathic pain

KW - Treatment

UR - http://www.scopus.com/inward/record.url?scp=85032023392&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85032023392&partnerID=8YFLogxK

U2 - 10.1016/j.jtos.2017.10.001

DO - 10.1016/j.jtos.2017.10.001

M3 - Review article

C2 - 29031645

AN - SCOPUS:85032023392

VL - 16

SP - 31

EP - 44

JO - Ocular Surface

JF - Ocular Surface

SN - 1542-0124

IS - 1

ER -

Access to Document