Neuropathic pain and dry eye

Anat Galor, Hamid Reza Moein, Charity Lee, Adriana Rodriguez, Elizabeth R. Felix, Konstantinos D. Sarantopoulos, Roy C. Levitt

Research output: Contribution to journalReview articlepeer-review

45 Scopus citations

Abstract

Dry eye is a common, multifactorial disease currently diagnosed by a combination of symptoms and signs. Its epidemiology and clinical presentation have many similarities with neuropathic pain outside the eye. This review highlights the similarities between dry eye and neuropathic pain, focusing on clinical features, somatosensory function, and underlying pathophysiology. Implications of these similarities on the diagnosis and treatment of dry eye are discussed.

Original languageEnglish (US)
Pages (from-to)31-44
Number of pages14
JournalOcular Surface
Volume16
Issue number1
DOIs
StatePublished - Jan 2018

Keywords

  • Dry eye
  • Genetics
  • Inflammation
  • Nerve sensitization
  • Neuropathic pain
  • Treatment

ASJC Scopus subject areas

  • Ophthalmology

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