Neuronal functional connectivity dynamics in cortex: An MSC-based analysis

Lin Li, Il Park, Sohan Seth, Justin C. Sanchez, José C. Príncipe

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

The activation of neural ensembles in the cortex is correlated with behavioral states and a change in neuronal functional connectivity patterns is expected. In this paper, we investigate this dynamic nature of functional connectivity in the cortex. Because of the time scale of behavior, a robust method with limited sample size is desirable. In light of this, we utilize mean square contingency (MSC) to measure the pairwise neural dependency to quantify the cortical functional connectivity. Simulation results show that MSC is more robust than cross correlation when the sample size is small. In monkey neural data test, our approach is more effective in detecting the dynamics of functional connectivity associated with the transitions between rest and movement states.

Original languageEnglish (US)
Title of host publication2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
Pages4136-4139
Number of pages4
DOIs
StatePublished - Dec 1 2010
Event2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 - Buenos Aires, Argentina
Duration: Aug 31 2010Sep 4 2010

Publication series

Name2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10

Other

Other2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10
CountryArgentina
CityBuenos Aires
Period8/31/109/4/10

ASJC Scopus subject areas

  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Health Informatics

Cite this

Li, L., Park, I., Seth, S., Sanchez, J. C., & Príncipe, J. C. (2010). Neuronal functional connectivity dynamics in cortex: An MSC-based analysis. In 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10 (pp. 4136-4139). [5627362] (2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10). https://doi.org/10.1109/IEMBS.2010.5627362