Neurological potassium channelopathies

Research output: Contribution to journalReview article

31 Scopus citations

Abstract

Potassium channel dysfunction has been implicated in a variety of genetic and acquired neurological disorders that are collectively referred to as the potassium channelopathies. These include acquired neuromyotonia, episodic ataxia type-1, hereditary deafness syndromes, benign familial neonatal convulsions and hypokalaemic periodic paralysis. Insight into potassium channel structure and function is crucial to understanding the pathophysiology of these conditions. This article describes potassium channel structure and function and then outlines what is known about the immunology and genetics of the neurological potassium channelopathies.

Original languageEnglish (US)
Pages (from-to)787-797
Number of pages11
JournalQJM - Monthly Journal of the Association of Physicians
Volume93
Issue number12
DOIs
StatePublished - Jan 1 2000
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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