Neurological and magnetic resonance imaging findings in children with developmental language impairment

Richard I. Webster, Caroline Erdos, Karen Evans, Annette Majnemer, Gaurav Saigal, Eva Kehayia, Elin Thordardottir, Alan Evans, Michael I. Shevell

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Neurologic and radiologic findings in children with well-defined developmental language impairment have rarely been systematically assessed. Children aged 7 to 13 years with developmental language impairment or normal language (controls) underwent language, nonverbal cognitive, motor and neurological assessments, standardized assessment for subtle neurological signs, and magnetic resonance imaging. Nine children with developmental language impairment and 12 controls participated. No focal abnormalities were identified on standard neurological examination. Age and developmental language impairment were independent predictors of neurological subtle signs scores (r2 = 0.52). Imaging abnormalities were identified in two boys with developmental language impairment and no controls (P = .17). Lesions identified were predicted neither by history nor by neurological examination. Previously unsuspected lesions were identified in almost 25% of children with developmental language impairment. Constraints regarding cooperation and sedation requirements may limit the clinical application of imaging modalities in this population.

Original languageEnglish (US)
Pages (from-to)870-877
Number of pages8
JournalJournal of child neurology
Volume23
Issue number8
DOIs
StatePublished - Aug 2008

Keywords

  • Imaging
  • Language impairment

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health

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    Webster, R. I., Erdos, C., Evans, K., Majnemer, A., Saigal, G., Kehayia, E., Thordardottir, E., Evans, A., & Shevell, M. I. (2008). Neurological and magnetic resonance imaging findings in children with developmental language impairment. Journal of child neurology, 23(8), 870-877. https://doi.org/10.1177/0883073808315620