Abstract
Neurologic disease was the harbinger of the acquired immunodeficiency syndrome (AIDS) in 26 (20%) of 132 patients and ultimately developed in 83 (63%). The most common neurologic disorder heralding AIDS was toxoplasmic encephalitis (17 cases) followed by cryptococcal meningitis (six), retinitis (three), progressive multifocal leukoencephalopathy (two), neuropathy (one), myopathy (one), and subacute 'viral' encephalitis (one). In four patients, more than one neurologic disorder coexisted at presentation. Recognition of underlying human T cell lymphotropic virus type III (HTLV-III) infection may allow a more expedient determination of the cause of the neurologic disease. Our study emphasizes the importance of testing for the presence of HTLV-III antibody and assessing the immunologic status of all patients at risk for AIDS who have neurologic illness.
| Original language | English |
|---|---|
| Pages (from-to) | 683-686 |
| Number of pages | 4 |
| Journal | Southern Medical Journal |
| Volume | 80 |
| Issue number | 6 |
| State | Published - Dec 1 1987 |
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ASJC Scopus subject areas
- Medicine(all)
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Neurologic disease as the presenting manifestation of acquired immunodeficiency syndrome. / Berger, J. R.; Moskowitz, L.; Fischl, Margaret A; Kelley, R. E.
In: Southern Medical Journal, Vol. 80, No. 6, 01.12.1987, p. 683-686.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Neurologic disease as the presenting manifestation of acquired immunodeficiency syndrome
AU - Berger, J. R.
AU - Moskowitz, L.
AU - Fischl, Margaret A
AU - Kelley, R. E.
PY - 1987/12/1
Y1 - 1987/12/1
N2 - Neurologic disease was the harbinger of the acquired immunodeficiency syndrome (AIDS) in 26 (20%) of 132 patients and ultimately developed in 83 (63%). The most common neurologic disorder heralding AIDS was toxoplasmic encephalitis (17 cases) followed by cryptococcal meningitis (six), retinitis (three), progressive multifocal leukoencephalopathy (two), neuropathy (one), myopathy (one), and subacute 'viral' encephalitis (one). In four patients, more than one neurologic disorder coexisted at presentation. Recognition of underlying human T cell lymphotropic virus type III (HTLV-III) infection may allow a more expedient determination of the cause of the neurologic disease. Our study emphasizes the importance of testing for the presence of HTLV-III antibody and assessing the immunologic status of all patients at risk for AIDS who have neurologic illness.
AB - Neurologic disease was the harbinger of the acquired immunodeficiency syndrome (AIDS) in 26 (20%) of 132 patients and ultimately developed in 83 (63%). The most common neurologic disorder heralding AIDS was toxoplasmic encephalitis (17 cases) followed by cryptococcal meningitis (six), retinitis (three), progressive multifocal leukoencephalopathy (two), neuropathy (one), myopathy (one), and subacute 'viral' encephalitis (one). In four patients, more than one neurologic disorder coexisted at presentation. Recognition of underlying human T cell lymphotropic virus type III (HTLV-III) infection may allow a more expedient determination of the cause of the neurologic disease. Our study emphasizes the importance of testing for the presence of HTLV-III antibody and assessing the immunologic status of all patients at risk for AIDS who have neurologic illness.
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M3 - Article
C2 - 3473692
AN - SCOPUS:0023481927
VL - 80
SP - 683
EP - 686
JO - Southern Medical Journal
JF - Southern Medical Journal
SN - 0038-4348
IS - 6
ER -