Neurologic disease as the presenting manifestation of acquired immunodeficiency syndrome

J. R. Berger, L. Moskowitz, Margaret A Fischl, R. E. Kelley

Research output: Contribution to journalArticle

92 Citations (Scopus)

Abstract

Neurologic disease was the harbinger of the acquired immunodeficiency syndrome (AIDS) in 26 (20%) of 132 patients and ultimately developed in 83 (63%). The most common neurologic disorder heralding AIDS was toxoplasmic encephalitis (17 cases) followed by cryptococcal meningitis (six), retinitis (three), progressive multifocal leukoencephalopathy (two), neuropathy (one), myopathy (one), and subacute 'viral' encephalitis (one). In four patients, more than one neurologic disorder coexisted at presentation. Recognition of underlying human T cell lymphotropic virus type III (HTLV-III) infection may allow a more expedient determination of the cause of the neurologic disease. Our study emphasizes the importance of testing for the presence of HTLV-III antibody and assessing the immunologic status of all patients at risk for AIDS who have neurologic illness.

Original languageEnglish
Pages (from-to)683-686
Number of pages4
JournalSouthern Medical Journal
Volume80
Issue number6
StatePublished - Dec 1 1987

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Nervous System Diseases
Acquired Immunodeficiency Syndrome
HIV
Viral Encephalitis
Cryptococcal Meningitis
Progressive Multifocal Leukoencephalopathy
Retinitis
HIV Antibodies
Muscular Diseases
Encephalitis
Nervous System
HIV Infections

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Neurologic disease as the presenting manifestation of acquired immunodeficiency syndrome. / Berger, J. R.; Moskowitz, L.; Fischl, Margaret A; Kelley, R. E.

In: Southern Medical Journal, Vol. 80, No. 6, 01.12.1987, p. 683-686.

Research output: Contribution to journalArticle

Berger, J. R. ; Moskowitz, L. ; Fischl, Margaret A ; Kelley, R. E. / Neurologic disease as the presenting manifestation of acquired immunodeficiency syndrome. In: Southern Medical Journal. 1987 ; Vol. 80, No. 6. pp. 683-686.
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