Neurogenesis: Is the Adult Stem Cell Young or Old?

Jerome Ricard, Daniel J. Liebl

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations

Abstract

Stem cell biology is one of the most exciting, controversial, and debated fields in science today. It has been suggested that neuronal replacement therapy using stem cell transplants may be one possible answer to a host of neuropathological disorders including spinal cord injury, stroke, and neurodegenerative diseases. Important sources for stem cells include the developing embryo and adult central nervous system, but will these populations of cells exhibit similar behavior and responses to stimuli? This review will discuss some important similarities and differences between the embryonic and adult stem cell, as well as the basis for developing therapeutic approaches for stem cell replacement.

Original languageEnglish (US)
Pages (from-to)1-6
Number of pages6
JournalIUBMB life
Volume56
Issue number1
DOIs
StatePublished - Jan 2004

Keywords

  • Differentiation
  • Migration
  • Neuroblast
  • Proliferation
  • Stem cells
  • Subventricular zone

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

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