Neurogenesis: Is the Adult Stem Cell Young or Old?

Jerome Ricard; Daniel J. Liebl

doi:10.1080/15216540310001659452

Neurogenesis: Is the Adult Stem Cell Young or Old?

Jerome Ricard, Daniel J. Liebl

Neurological Surgery

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

Stem cell biology is one of the most exciting, controversial, and debated fields in science today. It has been suggested that neuronal replacement therapy using stem cell transplants may be one possible answer to a host of neuropathological disorders including spinal cord injury, stroke, and neurodegenerative diseases. Important sources for stem cells include the developing embryo and adult central nervous system, but will these populations of cells exhibit similar behavior and responses to stimuli? This review will discuss some important similarities and differences between the embryonic and adult stem cell, as well as the basis for developing therapeutic approaches for stem cell replacement.

Original language	English (US)
Pages (from-to)	1-6
Number of pages	6
Journal	IUBMB life
Volume	56
Issue number	1
DOIs	https://doi.org/10.1080/15216540310001659452
State	Published - Jan 2004

Keywords

Differentiation
Migration
Neuroblast
Proliferation
Stem cells
Subventricular zone

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Genetics
Cell Biology

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KW - Proliferation

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KW - Subventricular zone

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Neurogenesis: Is the Adult Stem Cell Young or Old?

Abstract

Keywords

ASJC Scopus subject areas

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