Neurogenesis from stem cells

Veronica R. Fortino; Devon Pawley; Nastasja Ecker; Zenith Acosta; Juan A. Kochen; Herman S. Cheung

doi:10.2174/2210296504666140214200150

Neurogenesis from stem cells

Veronica R. Fortino, Devon Pawley, Nastasja Ecker, Zenith Acosta, Juan A. Kochen, Herman S. Cheung

Biomedical Engineering

Research output: Contribution to journal › Review article › peer-review

Abstract

This review discusses the present field of neurogenesis using adult stem cells. The authors highlight different methods of differentiating adult stem cells into neural cells: Growth factor and chemical induction, transfection, scaffold and/or 3D culture, and bioreactor and external stimuli. These different methods will be discussed using relevant patents and recent (< 5 year) scientific literature. Additionally, the authors present where they believe the future of neurogenesis from stem cells is headed - the use of neural crest stem cells as the ideal cell source for neurogenesis.

Original language	English (US)
Pages (from-to)	16-33
Number of pages	18
Journal	Recent Patents on Regenerative Medicine
Volume	4
Issue number	1
DOIs	https://doi.org/10.2174/2210296504666140214200150
State	Published - Jan 1 2014

Keywords

Differentiation
Neural crest stem cells
Neuro-induction
Neurogenesis
Stem cells

ASJC Scopus subject areas

Developmental Neuroscience
Cell Biology
Developmental Biology

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abstract = "This review discusses the present field of neurogenesis using adult stem cells. The authors highlight different methods of differentiating adult stem cells into neural cells: Growth factor and chemical induction, transfection, scaffold and/or 3D culture, and bioreactor and external stimuli. These different methods will be discussed using relevant patents and recent (< 5 year) scientific literature. Additionally, the authors present where they believe the future of neurogenesis from stem cells is headed - the use of neural crest stem cells as the ideal cell source for neurogenesis.",

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AU - Pawley, Devon

AU - Ecker, Nastasja

AU - Acosta, Zenith

AU - Kochen, Juan A.

AU - Cheung, Herman S.

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AB - This review discusses the present field of neurogenesis using adult stem cells. The authors highlight different methods of differentiating adult stem cells into neural cells: Growth factor and chemical induction, transfection, scaffold and/or 3D culture, and bioreactor and external stimuli. These different methods will be discussed using relevant patents and recent (< 5 year) scientific literature. Additionally, the authors present where they believe the future of neurogenesis from stem cells is headed - the use of neural crest stem cells as the ideal cell source for neurogenesis.

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KW - Neuro-induction

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